Kernif T., Medrouh B., Eddaikra N., Oury Bruno, Holzmuller P., Sereno Denis. (2024). Ticks as vectors of Trypanosomatidae with medical or veterinary interest : insights and implications from a comprehensive systematic review and meta-analysis. Heliyon, 10 (24), e40895 [31 p.]. ISSN 2405-8440.
Titre du document
Ticks as vectors of Trypanosomatidae with medical or veterinary interest : insights and implications from a comprehensive systematic review and meta-analysis
Since the 20th century, numerous studies have detected or isolated parasites from the Trypanosomatidae family in various tick species. However, the status of ticks as vectors for medically or
veterinary significant Trypanosoma and Leishmania remains unclear. We conducted a systematic review and meta-analysis to provide new insights into the potential vector status of these path-
ogens, which have significant medical and veterinary implications. We searched three databases (PubMed, Google Scholar, and Web of Science) from 1912 to June 30, 2023, resulting in 94
papers included in the qualitative analysis and 86 papers in the quantitative analysis. All identified field studies were conducted in endemic areas and investigated the presence of Trypanosoma
and Leishmania parasites, DNA, or antigens in ticks. We recorded a pooled prevalence of Trypanosomatidae detection in ticks at 15.48 % [7.99-24.61 %], with significant variations depending
on the year, detection method, and geographical area. Most of the infected tick species belonged to the genera Amblyomma, Hyalomma, Ixodes, and Rhipicephalus. Experimental laboratory work on
transmission routes demonstrated potential vector competence in both the Argasidae and Ixodidae tick families. Although our systematic review and meta-analysis provide compelling evidence
of the natural infection of ticks by Trypanosomatidae parasites, along with some evidence of non-traditional transmission routes, they do not offer conclusive evidence regarding the role of ticks as
biological or mechanical vectors for Trypanosomatidae species of veterinary and medical interest. This highlights the urgent need for additional investigations to address this point.
Plan de classement
Epidémiologie des trypanosomiases [052GLOTRY02]
;
Tiques et autres acariens / Divers [052TIAC]
;
Maladies des animaux [080PROANI05]
