Bonguili N. C. B., Mombo I. M., Lenguiya L. H., Lattaphasavang V., Pabouriboune P., Deharo Eric, Fritz M., Lyelet J. E. D., Elguero Eric, Koukouikila-Koussounda F., Mayengue P. I., Leroy Eric, Niama R. F., Locatelli Sabrina. (2025). Etiology and epidemiology of respiratory infections in community-based influenza-like illness during the COVID-19 pandemic, Vientiane, Lao People's Democratic Republic. International Journal of Infectious Diseases, 161, 108079 [8 p.]. ISSN 1201-9712.
Titre du document
Etiology and epidemiology of respiratory infections in community-based influenza-like illness during the COVID-19 pandemic, Vientiane, Lao People's Democratic Republic
Année de publication
2025
Auteurs
Bonguili N. C. B., Mombo I. M., Lenguiya L. H., Lattaphasavang V., Pabouriboune P., Deharo Eric, Fritz M., Lyelet J. E. D., Elguero Eric, Koukouikila-Koussounda F., Mayengue P. I., Leroy Eric, Niama R. F., Locatelli Sabrina
Source
International Journal of Infectious Diseases, 2025,
161, 108079 [8 p.] ISSN 1201-9712
Objectives: Respiratory infections pose an ongoing global public health burden, with multiple viral and bacterial etiologies. This study aimed to characterize the etiology of influenza-like illness (ILI) during the COVID-19 pandemic in a community cohort in Vientiane, Lao People's Democratic Republic (Lao PDR). Methods: From September 2021 to April 2022, 6300 individuals from 999 households in 25 villages were enrolled in a prospective surveillance study. Oropharyngeal swabs were collected from ILI cases and tested for SARS-CoV-2 using reverse transcription-polymerase chain reaction, and for 21 additional respiratory pathogens using a multiplex panel. Results: Among 462 samples analyzed, 360 (77.92%) were positive for at least one pathogen, including 338 viral and 79 bacterial infections. SARS-CoV-2 was predominant (67.53%), followed by Staphylococcus aureus (12.55%), human rhinovirus (6.93%), and Streptococcus pneumoniae (5.41%). Seasonal viruses, such as influenza A/B, respiratory syncytial virus, human parainfluenza virus, and human metapneumovirus were notably absent. Co-infections occurred in 21.21% of cases, with lower rates among SARS-CoV-2-positive individuals. Conclusions: These findings highlight the dominance of SARS-CoV-2 and the suppression of typical seasonal viruses, likely due to public health measures and viral interference. The results emphasize the importance of multiplex, community-level surveillance to understand respiratory pathogen dynamics and to strengthen preparedness in resource-limited settings.
Plan de classement
Santé : généralités [050]
;
Entomologie médicale / Parasitologie / Virologie [052]
Description Géographique
LAOS
Localisation
Fonds IRD [F B010095493]
Identifiant IRD
fdi:010095493
