Appenzeller J., Tilvi S., Martin M. T., Gallard J. F., El-bitar H., Dau E. T. H., Debitus Cécile, Laurent Dominique, Moriou C., Al-Mourabit A. (2009). Benzosceptrins A and B with a unique benzocyclobutane skeleton and nagelamide S and T from Pacific sponges. Organic Letters, 11 (21), p. 4874-4877. ISSN 1523-7060.
Titre du document
Benzosceptrins A and B with a unique benzocyclobutane skeleton and nagelamide S and T from Pacific sponges
Appenzeller J., Tilvi S., Martin M. T., Gallard J. F., El-bitar H., Dau E. T. H., Debitus Cécile, Laurent Dominique, Moriou C., Al-Mourabit A.
Source
Organic Letters, 2009,
11 (21), p. 4874-4877 ISSN 1523-7060
Four new dimeric pyrrole-2-aminoimidazole alkaloids have been isolated from the Pacific marine sponges Agelas cf. mauritiana and Phakellia sp. They include the unusual C2 symmetrical benzosceptrins A (4) and B (5), which each possess a unique benzocyclobutane skeleton and nagelamides S (6) and T (7). Their structures and relative configuration were elucidated from spectroscopic data. Plausible biogenetic paths for these compounds are also proposed in this paper.
