Prevention of mother-to-child transmission of HIV at the second immunization visit : a cross-sectional study, Burkina Faso

2022

Article référencé dans le Web of Science WOS:000923446600016

Sakana B. Leticia D., Mennecier A., Fao P., Tassembedo S., Moles J.-P., Kania D., Taofiki A. O., Kadeba F. E., Diallo I., Eymard-Duvernay Sabrina, D'Ottavi M., Meda N., Mosqueira B., Van de Perre P., Nagot N., ANRS 12388 PREVENIR-PEV Study Group

Bulletin of the World Health Organization, 2022, 100 (12), 769-776 ISSN 0042-9686

Objective : To evaluate the performance of the cascade of activities for prevention of mother-to-child transmission (PMTCT) of human immunodeficiency virus (HIV) at the second immunization visit in Burkina Faso. Methods : In a cross-sectional study, we recruited mothers attending the second immunization visit for their infant in 20 health centres of Bobo-Dioulasso city, Burkina Faso over 12 months (2019-2020). We administered a short questionnaire to 14 176 mothers and performed HIV serological tests on mothers who had not been tested in the last 3 months. All mothers were asked about their attendance for antenatal care and HIV rapid testing. HIV-infected mothers were also asked about the timing of their HIV diagnosis, antiretroviral therapy, pre-exposure prophylaxis initiation at birth and infant diagnosis of HIV. Findings Of 14 136 respondents, 13 738 (97.2%) had at least one HIV serological test in their lifetime. Of 13 078 mothers who were never tested or were HIV-negative, 12 454 (95.2%) were tested during or after their last pregnancy. Among HIV-infected mothers already aware of their status, 110/111 (99.1%) women were on antiretroviral therapy. Among HIV-exposed infants, 84/101 (83.2%) babies received 6 weeks of antiretroviral prophylaxis at birth and 58/110 (52.7%) had a blood sample collected for early infant diagnosis. Only two mothers received their child's test results at the time of the second immunization visit. Four mothers were newly diagnosed as HIV-positive during the study. Conclusion : Collecting data at the second immunization visit, a visit rarely missed by mothers, could be useful for identifying gaps in the PMTCT cascade in settings where mothers are difficult to reach, such as in low-income countries with intermediate or low HIV prevalence.

Médecine [050MEDECI] ; Maladies sexuellement transmissibles [052MALTRA03]

Fonds IRD [F B010090459]

fdi:010090459