@article{fdi:010087565,
  title = {{A}daptation strategies to high hydrostatic pressures in {P}seudothermotoga species revealed by transcriptional analyses},
  author = {{F}enouil, {R}. and {P}radel, {N}athalie and {B}elahbib, {H}. and {R}oumagnac, {M}. and {B}artoli, {M}. and {B}en {H}ania, {W}. and {D}enis, {Y}. and {G}arel, {M}. and {T}amburini, {C}. and {O}llivier, {B}ernard and {S}ummers, {Z}. and {A}rmougom, {F}abrice and {D}olla, {A}.},
  editor = {},
  language = {{ENG}},
  abstract = {{P}seudothermotoga elfii strain {DSM}9442 and {P}. elfii subsp. lettingae strain {DSM}14385 are hyperthermophilic bacteria. {P}. elfii {DSM}9442 is a piezophile and was isolated from a depth of over 1600 m in an oil-producing well in {A}frica. {P}. elfii subsp. lettingae is piezotolerant and was isolated from a thermophilic bioreactor fed with methanol as the sole carbon and energy source. {I}n this study, we analyzed both strains at the genomic and transcriptomic levels, paying particular attention to changes in response to pressure increases. {T}ranscriptomic analyses revealed common traits of adaptation to increasing hydrostatic pressure in both strains, namely, variations in transport membrane or carbohydrate metabolism, as well as species-specific adaptations such as variations in amino acid metabolism and transport for the deep {P}. elfii {DSM}9442 strain. {N}otably, this work highlights the central role played by the amino acid aspartate as a key intermediate of the pressure adaptation mechanisms in the deep strain {P}. elfii {DSM}9442. {O}ur comparative genomic and transcriptomic analysis revealed a gene cluster involved in lipid metabolism that is specific to the deep strain and that was differentially expressed at high hydrostatic pressures and might, thus, be a good candidate for a piezophilic gene marker in {P}seudothermotogales.},
  keywords = {hydrostatic pressure ; adaptation ; {P}seudothermotoga sp},
  booktitle = {},
  journal = {{M}icroorganisms},
  volume = {11},
  numero = {3},
  pages = {773 [17 ]},
  year = {2023},
  DOI = {10.3390/microorganisms11030773},
  URL = {https://www.documentation.ird.fr/hor/fdi:010087565},
}