@article{fdi:010086827,
  title = {{M}olecular prevalence, genetic characterization and patterns of {T}oxoplasma gondii infection in domestic small mammals from {C}otonou, {B}enin},
  author = {{E}tougbetche, {J}. {R}. and {H}amidovic, {A}. and {D}ossou, {H}. {J}. and {C}oan-{G}rosso, {M}. and {R}oques, {R}. and {P}lault, {N}. and {H}ouemenou, {G}. and {B}adou, {S}. and {M}issihoun, {A}. {A}. and {K}arim, {I}. {Y}. {A}. and {G}alal, {L}okman and {D}iagne, {C}hristophe {A}midi and {D}arde, {M}. {L}. and {D}obigny, {G}authier and {M}ercier, {A}.},
  editor = {},
  language = {{ENG}},
  abstract = {{T}oxoplasmosis, one of the most prevalent parasitic infections in humans and animals, is caused by the intracellular protozoan parasite {T}oxoplasma gondii. {S}mall mammals play a key role as intermediate reservoir hosts in the maintenance of the {T}. gondii life cycle. {I}n this study, we estimated the molecular prevalence and provide genetic diversity data for {T}. gondii in 632 small mammals sampled in four areas of {C}otonou city, {B}enin. {B}oth the brain and heart of each individual were screened through {T}. gondii-targeting q{PCR}, and positive samples were then genotyped using a set of 15 {T}. gondii-specific microsatellites. {P}revalence data were statistically analyzed in order to assess the relative impact of individual host characteristics, spatial distribution, composition of small mammal community, and urban landscape features. {A}n overall {T}. gondii molecular prevalence of 15.2% was found and seven genotypes, all belonging to the {A}frica 1 lineage, could be retrieved from the invasive black rat {R}attus rattus and the native {A}frican giant shrew {C}rocidura olivieri. {S}tatistical analyses did not suggest any significant influence of the environmental parameters used in this study. {R}ather, depending on the local context, {T}. gondii prevalence appeared to be associated either with black rat, shrew, or mouse abundance or with the trapping period. {O}verall, our results highlight the intricate relationships between biotic and abiotic factors involved in {T}. gondii epidemiology and suggest that {R}. rattus and {C}. olivieri are two competent reservoirs for the {A}frica 1 lineage, a widespread lineage in tropical {A}frica and the predominant lineage in {B}enin.},
  keywords = {{T}oxoplasma gondii ; {S}mall mammals ; {P}arasite ecology ; {I}nfectious disease ; {M}olecular epidemiology ; {U}rban eco-epidemiology ; {B}enin ; {BENIN} ; {COTONOU}},
  booktitle = {},
  journal = {{P}arasite},
  volume = {29},
  numero = {},
  pages = {58 [13 p.]},
  ISSN = {1252-607{X}},
  year = {2022},
  DOI = {10.1051/parasite/2022058},
  URL = {https://www.documentation.ird.fr/hor/fdi:010086827},
}