%0 Journal Article
%9 ACL : Articles dans des revues avec comité de lecture répertoriées par l'AERES
%A Goumballa, N.
%A Sambou, M.
%A Samba, D. F.
%A Bassene, H.
%A Bedotto, M.
%A Aidara, A.
%A Dieng, M.
%A Hoang, V. T.
%A Parola, P.
%A Sokhna, Cheikh
%A Gautret, P.
%T PCR investigation of infections in patients consulting at a healthcare centre over a four-year period during the Grand Magal of Touba
%D 2023
%L fdi:010086766
%G ENG
%J Travel Medicine and Infectious Disease
%@ 1477-8939
%K Febrile systemic illness ; Gastrointestinal infections ; Grand Magal ; Patients ; PCR ; Respiratory infections
%K SENEGAL
%M ISI:000901102300002
%P 102515 [7 ]
%R 10.1016/j.tmaid.2022.102515
%U https://www.documentation.ird.fr/hor/fdi:010086766
%> https://horizon.documentation.ird.fr/exl-doc/pleins_textes/2023-02/010086766.pdf
%V 52
%W Horizon (IRD)
%X Background: Respiratory and gastrointestinal symptoms and febrile illness are the most common complaints among ill pilgrims attending the Grand Magal of Touba (GMT) in Senegal. Methods: Patients presenting with respiratory or gastrointestinal symptoms or febrile systemic illnesses were recruited between 2018 and 2021 at a healthcare centre close to Touba. Respiratory, gastrointestinal and blood samples were tested for potential pathogens using qPCR.Results: 538 patients were included. 45.5% of these were female, with a median age of 17 years. Of the 326 samples collected from patients with a cough, 62.8% tested positive for at least one virus, including influenza viruses (33.1%). A high positivity rate of bacterial carriage was observed for Haemophilus influenzae (72.7%), Streptococcus pneumoniae (51.2%) and Moraxella catarrhalis (46.0%). Of the 95 samples collected from patients with diarrhoea, 71.3% were positive, with high rates of bacterial carriage, ranging from 4.2% for Tropheryma whipplei to 45.3% for Entero-pathogenic Escherichia coli. Of the 141 blood samples collected from patients with fever, 31.9% were positive including Plasmodium falciparum (21.3%), Borrelia sp. (5.7%) and dengue virus (5.0%). Conclusion: This study provides insight into the aetiology of most common infections at the GMT on which to base therapeutic options.
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