@article{fdi:010086260,
  title = {{T}he threat of multiple liver carcinogens in the population of {L}aos : a review},
  author = {{S}itbounlang, {P}. and {M}archio, {A}. and {D}eharo, {E}ric and {P}aboriboune, {P}. and {P}ineau, {P}.},
  editor = {},
  language = {{ENG}},
  abstract = {{L}aos is a landlocked country in {S}outh {E}ast {A}sia, ranking fifth for primary liver cancer incidence worldwide. {R}isk factors that might explain this worrying situation are poorly known. {W}e conducted a review of the literature concerning the etiologies of terminal liver diseases in {L}aos. {A} double infectious burden with hepatitis {B} and {C} viruses and the liver fluke {O}pisthorchis viverrini seems to be the main cause of the high liver cancer incidence. {M}oreover, it was also suggested that mutagenic substances frequently found in tobacco, alcoholic beverages, fermented fish, and mold-contaminated cereals or nuts, which are all substances heavily consumed by {L}ao people, lead to the accumulation of {DNA} mutations in the liver cell genome causing tumor processes. {H}owever, the respective proportions of liver cancer cases attributable to each category of infections and substances consumed, as well as the histological nature of the neoplasia are still not precisely documented in {L}aos. {T}he international medical and scientific communities as well as public health stakeholders should urgently consider the alarming situation of liver health in {L}aos to stimulate both research and subsequent implementation of prevention policies.},
  keywords = {{LAOS} ; {CAMBODGE} ; {MYANMAR} ; {THAILANDE} ; {VIET} {NAM} ; {CHINE} ; {YUNNAN}},
  booktitle = {},
  journal = {{L}ivers},
  volume = {1},
  numero = {1},
  pages = {49--59},
  ISSN = {2673-4389},
  year = {2021},
  DOI = {10.3390/livers1010005},
  URL = {https://www.documentation.ird.fr/hor/fdi:010086260},
}