@article{fdi:010085935,
  title = {{D}ifferential preferences for {RBC}s is key for {P}lasmodium species evolutionary diversity within human host},
  author = {{D}jidjou-{D}emasse, {R}ams{\`e}s and {M}ann-{M}anyombe, {M}. {L}. and {S}eydi, {O}. and {Y}atat-{D}jeumen, {V}.},
  editor = {},
  language = {{ENG}},
  abstract = {{P}lasmodium species exhibit differential preferences for red blood cells ({RBC}s) of different ages. {F}rom a fundamental standpoint, we propose an age-structured within-host malaria model taking into account the variation in {RBC}s preference. {W}e show that such a differential ecological characteristic of {P}lasmodium species within their human host is fundamental to capture species diversity within the same infected host individual. {W}e show that with such difference in the {RBC}s preferences, the long-term coexistence of different species is possible under a certain condition, basically based on a suitable order on the basic reproduction numbers of each species. {I}n particular, we show that the dynamical behavior of the model is not trivial and can range from the extinction of all species, the persistence of a single species, to the coexistence of more than one species. {W}e also describe how our general analysis can be applied in some coinfection configurations including three malaria species: {P}lasmodium falciparum, {P}lasmodium vivax, and/or {P}lasmodium malariae. {T}his improved understanding of the within-host parasite multiplication in a context of mixed {P}lasmodium species interactions.},
  keywords = {malaria ; mathematical modeling ; nonlinear dynamical system ; {RBC} ; preference ; within-host coexistence},
  booktitle = {},
  journal = {{S}tudies in {A}pplied {M}athematics},
  volume = {[{E}arly access]},
  numero = {},
  pages = {[30 ]},
  ISSN = {0022-2526},
  year = {2022},
  DOI = {10.1111/sapm.12527},
  URL = {https://www.documentation.ird.fr/hor/fdi:010085935},
}