Rate and predictors of ineffective HIV protection in African men who have sex with men taking pre-exposure prophylaxis

2022

Article référencé dans le Web of Science WOS:000787118400003

Eubanks A., Coulibaly B., Keita B. D., Anoma C., Dah T. E., Mensah E., Maradan G., Bourrelly M., Mora M., Riegel L., Castro D. R., Yaya Issifou, Spire B., Laurent Christian, Sagaon Teyssier Luis, CohMSM-PrEP Study Group

Aids and Behavior, 2022, [Early access], [14 p.] ISSN 1090-7165

We investigated the rate and predictors of ineffective HIV protection in men who have sex with men (MSM) taking pre-exposure prophylaxis (PrEP) in a prospective cohort study from November 2017 to November 2020 in Mali, Cote d'Ivoire, Burkina Faso, and Togo. MSM had to be 18 years or older and at high risk of HIV infection to participate. They also received a comprehensive sexual health prevention package, including PrEP, in community-based clinics as part of the cohort study. Using socio-behavioral/clinical data, HIV protection during their most recent anal intercourse with a male partner was categorized as effective or ineffective (i.e., incorrect PrEP adherence and no condom use). Seventeen percent (500/2839) of intercourses were ineffectively protected for the 520 study participants. Predictors of ineffective HIV protection included being an event-driven user with financial difficulties, having a high alcohol misuse score, and not being a member of a community association. PrEP programs in West Africa must be tailored to socially vulnerable MSM who struggle to adopt PrEP.

Entomologie médicale / Parasitologie / Virologie [052] ; Santé : aspects socioculturels, économiques et politiques [056]

AFRIQUE DE L'OUEST ; MALI ; COTE D'IVOIRE ; BURKINA FASO ; TOGO ; BAMAKO ; ABIDJAN ; OUAGADOUGOU ; LOME

Fonds IRD [F B010084712]

fdi:010084712