@article{fdi:010084238,
  title = {{M}onitoring insecticide resistance of adult and larval {A}edes aegypti ({D}iptera : {C}ulicidae) in {P}hnom {P}enh, {C}ambodia},
  author = {{B}oyer, {S}. and {M}aquart, {P}. {O}. and {C}hhuoy, {K}. and {S}uor, {K}. and {C}hhum, {M}. and {H}eng, {K}. and {L}eng, {S}. and {F}ontenille, {D}idier and {M}arcombe, {S}.},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ackground: {D}engue fever is a major public health concern in {C}ambodia, with thousands of cases every year in urban, suburban and rural areas of the country. {T}he main vector of dengue fever in {C}ambodia is {A}edes aegypti. {T}he organophosphate larvicide temephos and adulticides belonging to the pyrethrold family have been widely used for decades by public health authorities to fight dengue vectors, but resistance of {A}e. aegypti to these insecticides has been previously described for {C}ambodia. {M}ethods: {I}n order to adapt the vector control strategy presently used in {C}ambodia, we tested 14 adulticides belonging to the carbamate, organochlorine, organophosphate, and pyrethroid insecticide families and three larvicides [temephos, spinosad and {B}acillus thuringiensis ser. israelensis ({B}ti)] belonging to three different insecticide families (organophosphates, spinosyns and entomopathogenic bacteria). {T}he standard procedures used here to test the adults and larvae of an {A}e. aegypti population from {P}hnom {P}enh followed {W}orld {H}ealth {O}rganization guidelines. {R}esults: {F}or adults, high mortality rates were observed with carbamate, organophosphate and organochlorine (with the exception of dichlorodiphenyltrichloroethane) insecticides (i.e. between 87.6 and 100%), while low mortality rates were observed with all of the tested pyrethroid insecticides (i.e. between 1 and 35%). {F}or larvae, no resistance against {B}ti was detected [resistance ratio ({RR}90 < 1.6)], but moderate resistance was observed for temephos and spinosad ({RR}90 <5.6). {C}onclusions: {T}he results of this study indicate that (i) {B}ti should be considered a serious alternative to temephos for the control of {A}e. aegypti larvae; and (ii) the carbamate adulticides propoxur and bendiocarb should be employed instead of the widely used pyrethroid insecticides for the control of adult {A}e. aegypti on land under mosaic farming and crop rotation in {C}ambodia, as the insects were found to be resistant to the latter types of insecticide. {R}esearch focusing on insecticide resistance and innovative and effective vector control strategies should be undertaken as a public health priority in {C}ambodia.},
  keywords = {{CAMBODGE} ; {PHNOM} {PENH}},
  booktitle = {},
  journal = {{P}arasites and {V}ectors},
  volume = {15},
  numero = {1},
  pages = {44 [7 ]},
  ISSN = {1756-3305},
  year = {2022},
  DOI = {10.1186/s13071-022-05156-3},
  URL = {https://www.documentation.ird.fr/hor/fdi:010084238},
}