@article{fdi:010082465,
  title = {{D}efeating malaria in the {N}orth-{E}ast region : the forerunner for malaria elimination in {I}ndia},
  author = {{D}ev, {V}. and {M}anguin, {S}ylvie},
  editor = {},
  language = {{ENG}},
  abstract = {{I}ndia is a malaria endemic country which is targeting malaria elimination by 2027. {T}ransmission intensities are low-to-moderate depending on the region supported by multiple disease vectors. {A}mong these, comparatively {N}orth-{E}ast {I}ndia contributes to high proportions of malaria cases annually, the majority of which are due to {P}lasmodium falciparum (90/100). {A}nopheles minimus and {A}n. baimaii (sibling species in the {A}n. dirus complex) are widely prevalent and incriminated as vectors of malaria. {N}umber of intervention tools were field-evaluated beginning 1988 to date against disease vectors and causative parasites to contain the spread of malaria. {T}hese included (i) insecticide-treated netting materials ({ITN}s) for vector control, (ii) rapid diagnostic tests ({RDT}s) for in situ diagnosis, and (iii) therapeutic efficacy of artemisinin-based combination therapies ({ACT}s) for improved drug-policy; all of which were incorporated in healthcare services resulting in substantial disease transmission reduction. {P}opulations of both {A}n. minimus and {A}n. baimaii were observed depleting, instead {A}n. culicifacies s.l. recorded to be fast invading degraded forests and assessed to be resistant to multiple insecticides. {O}f the two prevalent {P}lasmodium species, while {P}. vivax continued to be susceptible to chloroquine therapy, {P}. falciparum had emerged resistant to most available antimalarial drugs except {ACT}s over space and time and spreading to peninsular {I}ndia threatening elimination efforts. {D}isease transmission trends were observed to be declining for which the  state of  {A}ssam has made huge strides reporting steady fall  in  cases each passing year vis-`a-vis {M}eghalaya, {M}izoram and {T}ripura (all sharing international border with {B}angladesh), in which malaria trans-mission remained uninterrupted. {C}onsequently, control of malaria in the {N}orth-{E}ast region of {I}ndia is of im-mediate importance and  needs prioritization for  intensified disease surveillance and  control interventions coupled with improved access to healthcare services mitigating risk of disease outbreaks and spread of drug- resistant malaria helping realize the goal of malaria elimination in the country.},
  keywords = {{INDE} ; {ASSAM}},
  booktitle = {},
  journal = {{A}cta {T}ropica},
  volume = {222},
  numero = {},
  pages = {106040 [10  en ligne]},
  ISSN = {0001-706{X}},
  year = {2021},
  DOI = {10.1016/j.actatropica.2021.106040},
  URL = {https://www.documentation.ird.fr/hor/fdi:010082465},
}