Publications des scientifiques de l'IRD

Medkour Hacène, Amona I., Akiana J., Laidoudi Y., Davoust B., Bitam I., Lafri I., Levasseur A., Diatta Georges, Sokhna Cheikh, Hernandez-Aguilar R. A., Barciela A., Gorsane S., Banga-Mboko H., Raoult D., Fenollar F., Mediannikov Oleg. (2021). Bacterial infections in humans and nonhuman primates from Africa : expanding the knowledge. Yale Journal of Biology and Medicine, 94 (2), p. 227-248. ISSN 0044-0086.

Titre du document
Bacterial infections in humans and nonhuman primates from Africa : expanding the knowledge
Année de publication
2021
Type de document
Article référencé dans le Web of Science WOS:000669540000005
Auteurs
Medkour Hacène, Amona I., Akiana J., Laidoudi Y., Davoust B., Bitam I., Lafri I., Levasseur A., Diatta Georges, Sokhna Cheikh, Hernandez-Aguilar R. A., Barciela A., Gorsane S., Banga-Mboko H., Raoult D., Fenollar F., Mediannikov Oleg
Source
Yale Journal of Biology and Medicine, 2021, 94 (2), p. 227-248 ISSN 0044-0086
The close phylogenetic relationship between humans and other primates creates exceptionally high potential for pathogen exchange. The surveillance of pathogens in primates plays an important role in anticipating possible outbreaks. In this study, we conducted a molecular investigation of pathogenic bacteria in feces from African nonhuman primates (NHPs). We also investigated the pathogens shared by the human population and gorillas living in the same territory in the Republic of Congo. In total, 93% of NHPs (n=176) and 95% (n=38) of humans were found to carry at least one bacterium. Non-pallidum Treponema spp. (including T. succinifaciens, T. berlinense, and several potential new species) were recovered from stools of 70% of great apes, 88% of monkeys, and 79% of humans. Non-tuberculosis Mycobacterium spp. were also common in almost all NHP species as well as in humans. In addition, Acinetobacter spp., members of the primate gut microbiota, were mainly prevalent in human and gorilla. Pathogenic Leptospira spp. were highly present in humans (82%) and gorillas (66%) stool samples in Congo, but were absent in the other NHPs, therefore suggesting a possible gorillas-humans exchange. Particular attention will be necessary for enteropathogenic bacteria detected in humans such as Helicobacter pylori, Salmonella spp. (including S. typhi/paratyphi), Staphyloccocus aureus, and Tropheryma whipplei, some of which were also present in gorillas in the same territory (S. aureus and T. whipplei). This study enhances our knowledge of pathogenic bacteria that threaten African NHPs and humans by using a non-invasive sampling technique. Contact between humans and NHPs results in an exchange of pathogens. Ongoing surveillance, prevention, and treatment strategies alone will limit the spread of these infectious agents.
Plan de classement
Santé : généralités [050] ; Entomologie médicale / Parasitologie / Virologie [052] ; Sciences du monde animal [080] ; Biotechnologies [084]
Description Géographique
SENEGAL ; CONGO ; ALGERIE ; DJIBOUTI
Localisation
Fonds IRD [F B010082299]
Identifiant IRD
fdi:010082299
Contact