@article{fdi:010082019, title = {{E}cology, evolution, and epidemiology of zoonotic and vector-borne infectious diseases in {F}rench {G}uiana : transdisciplinarity does matter to tackle new emerging threats}, author = {de {T}hoisy, {B}. and {D}uron, {O}. and {E}pelboin, {L}. and {M}usset, {L}. and {Q}u{\'e}nel, {P}. and {R}oche, {B}enjamin and {B}inetruy, {F}. and {B}riolant, {S}. and {C}arvalho, {L}. and {C}havy, {A}. and {C}ouppi{\'e}, {P}. and {D}emar, {M}. and {D}ouine, {M}. and {D}usfour, {I}. and {E}pelboin, {Y}. and {F}lamand, {C}. and {F}ranc, {A}. and {G}inouv{\`e}s, {M}. and {G}ourbi{\`e}re, {S}. and {H}ouel, {E}. and {K}ocher, {A}. and {L}avergne, {A}. and {L}e {T}urnier, {P}. and {M}athieu, {L}. and {M}urienne, {J}. and {N}acher, {M}. and {P}elleau, {S}. and {P}r{\'e}vot, {G}. and {R}ousset, {D}. and {R}oux, {E}mmanuel and {S}chaub, {R}. and {T}alaga, {S}. and {T}hill, {P}. and {T}irera, {S}. and {G}u{\'e}gan, {J}ean-{F}ran{\c{c}}ois}, editor = {}, language = {{ENG}}, abstract = {{F}rench {G}uiana is a {E}uropean ultraperipheric region located on the northern {A}tlantic coast of {S}outh {A}merica. {I}t constitutes an important forested region for biological conservation in the {N}eotropics. {A}lthough very sparsely populated, with its inhabitants mainly concentrated on the {A}tlantic coastal strip and along the two main rivers, it is marked by the presence and development of old and new epidemic disease outbreaks, both research and health priorities. {I}n this review paper, we synthetize 15 years of multidisciplinary and integrative research at the interface between wildlife, ecosystem modification, human activities and sociodemographic development, and human health. {T}his study reveals a complex epidemiological landscape marked by important transitional changes, facilitated by increased interconnections between wildlife, land-use change and human occupation and activity, human and trade transportation, demography with substantial immigration, and identified vector and parasite pharmacological resistance. {A}mong other {F}rench {G}uianese characteristics, we demonstrate herein the existence of more complex multi-host disease life cycles than previously described for several disease systems in {C}entral and {S}outh {A}merica, which clearly indicates that today the greater promiscuity between wildlife and humans due to demographic and economic pressures may offer novel settings for microbes and their hosts to circulate and spread. {F}rench {G}uiana is a microcosm that crystallizes all the current global environmental, demographic and socioeconomic change conditions, which may favor the development of ancient and future infectious diseases.}, keywords = {{GUYANE} {FRANCAISE} ; {AMAZONIE}}, booktitle = {}, journal = {{I}nfection, {G}enetics and {E}volution}, volume = {93}, numero = {}, pages = {104916 [18 ]}, ISSN = {1567-1348}, year = {2021}, DOI = {10.1016/j.meegid.2021.104916}, URL = {https://www.documentation.ird.fr/hor/fdi:010082019}, }