@article{fdi:010081007,
  title = {{R}hizobia use a pathogenic-like effector to hijack leguminous nodulation signalling},
  author = {{R}atu, {S}. {T}. {N}. and {T}eulet, {A}lbin and {M}iwa, {H}. and {M}asuda, {S}. and {N}guyen, {H}. {P}. and {Y}asuda, {M}. and {S}ato, {S}. and {K}aneko, {T}. and {H}ayashi, {M}. and {G}iraud, {E}ric and {O}kazaki, {S}.},
  editor = {},
  language = {{ENG}},
  abstract = {{L}egume plants form a root-nodule symbiosis with rhizobia. {T}his symbiosis establishment generally relies on rhizobium-produced {N}od factors ({NF}s) and their perception by leguminous receptors ({NFR}s) that trigger nodulation. {H}owever, certain rhizobia hijack leguminous nodulation signalling via their type {III} secretion system, which functions in pathogenic bacteria to deliver effector proteins into host cells. {H}ere, we report that rhizobia use pathogenic-like effectors to hijack legume nodulation signalling. {T}he rhizobial effector {B}el2-5 resembles the {X}op{D} effector of the plant pathogen {X}anthomonas campestris and could induce nitrogen-fixing nodules on soybean nfr mutant. {T}he soybean root transcriptome revealed that {B}el2-5 induces expression of cytokinin-related genes, which are important for nodule organogenesis and represses ethylene- and defense-related genes that are deleterious to nodulation. {R}emarkably, {B}el2-5 introduction into a strain unable to nodulate soybean mutant affected in {NF} perception conferred nodulation ability. {O}ur findings show that rhizobia employ and have customized pathogenic effectors to promote leguminous nodulation signalling.},
  keywords = {},
  booktitle = {},
  journal = {{S}cientific {R}eports - {N}ature},
  volume = {11},
  numero = {1},
  pages = {2034 [15 ]},
  ISSN = {2045-2322},
  year = {2021},
  DOI = {10.1038/s41598-021-81598-6},
  URL = {https://www.documentation.ird.fr/hor/fdi:010081007},
}