@article{fdi:010080636, title = {{T}hiamine fortification strategies in low- and middle-income settings : a review}, author = {{W}hitfield, {K}. {C}. and {S}mith, {T}. {J}. and {R}ohner, {F}. and {W}ieringa, {F}ranck and {G}reen, {T}. {J}.}, editor = {}, language = {{ENG}}, abstract = {{T}hiamine (vitamin {B}-1) is an essential micronutrient in energy metabolism and cognitive and neurological health. {T}hiamine deficiency disorders ({TDD}s) have a range of clinical presentations that result in various morbidities and can be fatal if not promptly recognized and treated, especially in infants. {T}o intervene, thiamine intakes by breastfeeding mothers and others at risk of thiamine deficiency should be increased to ensure adequate thiamine intake. {A}lthough thiamine fortification programs have a long history in high-income countries, there are few mandatory fortification programs to address {TDD}s in low- and middle-income countries ({LMIC}s), particularly in the regions of greatest concern, {S}outh and {S}outheast {A}sia. {T}his review highlights essential aspects for consideration in the development of a mandatory fortification program in {LMIC}s, including an overview of the data required to model fortification dosing schemes, available thiamine fortificants, and potential fortification vehicles, as well as identifies current knowledge gaps.}, keywords = {thiamine ; vitamin {B}-1 ; fortification ; enrichment ; thiamine deficiency disorders ; {MONDE}}, booktitle = {}, journal = {{A}nnals of the {N}ew {Y}ork {A}cademy of {S}ciences}, volume = {1498}, numero = {1}, pages = {29--45}, ISSN = {0077-8923}, year = {2021}, DOI = {10.1111/nyas.14565}, URL = {https://www.documentation.ird.fr/hor/fdi:010080636}, }