@article{fdi:010080616,
  title = {{E}pidemiology and prevalence of extended-spectrum beta-lactamase- and carbapenemase-producing {E}nterobacteriaceae in humans, animals and the environment in {W}est and {C}entral {A}frica},
  author = {{M}ahamat, {O}. {O}. and {K}empf, {M}. and {L}ounnas, {M}anon and {T}idjani, {A}. and {H}ide, {M}. and {B}enavides, {J}. {A}. and {C}arriere, {C}. and {B}anuls, {A}nne-{L}aure and {J}ean-{P}ierre, {H}. and {O}uedraogo, {A}. {S}. and {D}umont, {Y}. and {G}odreuil, {S}.},
  editor = {},
  language = {{ENG}},
  abstract = {{E}xtended-spectrum beta-lactamase-producing {E}nterobacteriaceae ({ESBL}-{E}) and carbapenemase-producing {E}nterobacteriaceae ({CPE}) are widespread. {H}ere we used the '{O}ne {H}ealth' approach to determine knowledge gaps on {ESBL}-{E} and {CPE} in {W}est and {C}entral {A}frica. {W}e searched all articles on {ESBL}-{E} and {CPE} in these {A}frican regions published in {P}ub{M}ed, {A}frican {J}ournals {O}nline and {G}oogle {S}cholar from 2000 onwards. {A}mong the 1201 articles retrieved, we selected 165 studies ({W}est {A}frica, 118; {C}entral {A}frica, 47) with data from 22 of the 26 {W}est and {C}entral {A}frica countries. {R}egarding the settings, 136 articles focused only on humans (carriage and/or infection), 6 articles on humans and animals, 13 on animals, 1 on humans and the environment, 8 on the environment and 1 on humans, animals and environments. {ESBL}-{E} prevalence ranged from 11-72% in humans and 7-79% in aquatic environments (wastewater). {I}n animals, {ESBL}-{E} prevalence hugely varied: 0% in cattle, 11-36% in chickens, 20% in rats, 21-71% in pigs and 32-75% in dogs. {T}he blu({CTX}-{M}-15) gene was the predominant {ESBL}-encoding gene and was associated with plasmids of incompatibility groups {F}, {H}, {K}, {Y}, {N}, {II} and {R}. {CPE} were studied only in humans. {C}lass {B} metallo-beta-lactamases ({NDM}) and class {D} oxacillinases ({OXA}-48 and {OXA}-181) were the most common carbapenemases. {O}ur results show major knowledge gaps, particularly on {ESBL} and {CPE} in animals and the environment, that might limit antimicrobial resistance management in these regions. {T}he results also emphasise the urgent need to improve active surveillance programmes in each country and to support antimicrobial stewardship.},
  keywords = {{ESBL} ; {C}arbapenemase ; {C}entral and {W}est {A}frica ; {E}nterobacteriaceae ; {D}ata ; {S}ystematic review ; {AFRIQUE} {CENTRALE} ; {AFRIQUE} {DE} {L}'{OUES}t},
  booktitle = {},
  journal = {{I}nternational {J}ournal of {A}ntimicrobial {A}gents},
  volume = {57},
  numero = {1},
  pages = {106203 [9 p.]},
  ISSN = {0924-8579},
  year = {2021},
  DOI = {10.1016/j.ijantimicag.2020.106203},
  URL = {https://www.documentation.ird.fr/hor/fdi:010080616},
}