@article{fdi:010080137, title = {{N}ovel {R}ickettsia genotypes in ticks in {F}rench {G}uiana, {S}outh {A}merica}, author = {{B}inetruy, {F}. and {B}uysse, {M}arie and {B}arosi, {R}. and {D}uron, {O}.}, editor = {}, language = {{ENG}}, abstract = {{R}ickettsia are obligate intracellular bacteria often associated with ticks and best known for causing human diseases (rickettsiosis), including typhus fever and sporadic cases of serious infection. {I}n this study, we conducted a large survey of ticks in {F}rench {G}uiana to understand the overall diversity of {R}ickettsia in this remote area largely covered by dense rainforests. {O}ut of 819 individuals (22 tick species in six genera), 252 (30.8%) samples were positive for {R}ickettsia infection. {M}ultilocus typing and phylogenetic analysis identified 19 {R}ickettsia genotypes, but none was 100% identical to already known {R}ickettsia species or strains. {A}mong these 19 genotypes, we identified two validated {R}ickettsia species, {R}ickettsia amblyommatis (spotted fever group) and {R}ickettsia bellii (bellii group), and characterized a novel and divergent {R}ickettsia phylogenetic group, the guiana group. {W}hile some tick hosts of these {R}ickettsia genotypes are among the most common ticks to bite humans in {F}rench {G}uiana, their potential pathogenicity remains entirely unknown. {H}owever, we found a strong association between {R}ickettsia genotypes and their host tick species, suggesting that most of these {R}ickettsia genotypes may be nonpathogenic forms maintained through transovarial transmission.}, keywords = {{GUYANE} {FRANCAISE}}, booktitle = {}, journal = {{S}cientific {R}eports}, volume = {10}, numero = {1}, pages = {2537 [11 ]}, ISSN = {2045-2322}, year = {2020}, DOI = {10.1038/s41598-020-59488-0}, URL = {https://www.documentation.ird.fr/hor/fdi:010080137}, }