%0 Journal Article
%9 ACL : Articles dans des revues avec comité de lecture répertoriées par l'AERES
%A Castelli, M.
%A Maurin, A.
%A Bartoli, A.
%A Dassa, M.
%A Marchi, B.
%A Finance, J.
%A Lagier, J. C.
%A Million, M.
%A Parola, P.
%A Brouqui, P.
%A Raoult, D.
%A Cortaredona, Sébastien
%A Jacquier, A.
%A Gaubert, J. Y.
%A Habert, P.
%T Prevalence and risk factors for lung involvement on low-dose chest CT (LDCT) in a paucisymptomatic population of 247 patients affected by covid-19 [+ Corrigendum , 2021, vol. 12, 21]
%D 2020
%L fdi:010080005
%G ENG
%J Insights into Imaging
%@ 1869-4101
%K COVID-19 ; Tomography ; X-ray computed ; Quantitative evaluation ; Pneumonia
%K FRANCE
%M ISI:000590208600001
%N 1
%P 117 [10  + Corrigendum , 2021, vol. 12, 21]
%U https://www.documentation.ird.fr/hor/fdi:010080005
%> https://horizon.documentation.ird.fr/exl-doc/pleins_textes/divers20-12/010080005.pdf
%V 11
%W Horizon (IRD)
%X Background Low-dose chest CT (LDCT) showed high sensitivity and ability to quantify lung involvement of COVID-19 pneumopathy. The aim of this study was to describe the prevalence and risk factors for lung involvement in 247 patients with a visual score and assess the prevalence of incidental findings. Methods For 12 days in March 2020, 250 patients with RT-PCR positive tests and who underwent LDCT were prospectively included. Clinical and imaging findings were recorded. The extent of lung involvement was quantified using a score ranging from 0 to 40. A logistic regression model was used to explore factors associated with a score >= 10. Results A total of 247 patients were analyzed; 138 (54%) showed lung involvement. The mean score was 4.5 +/- 6.5, and the mean score for patients with lung involvement was 8.1 +/- 6.8 [1-31]. The mean age was 43 +/- 15 years, with 121 males (48%) and 17 asymptomatic patients (7%). Multivariate analysis showed that age > 54 years (odds ratio 4.4[2.0-9.6] p < 0.001) and diabetes (4.7[1.0-22.1] p = 0.049) were risk factors for a score >= 10. Multivariate analysis including symptoms showed that only age > 54 years (4.1[1.7-10.0] p = 0.002) was a risk factor for a score >= 10. Rhinitis (0.3[0.1-0.7] p = 0.005) and anosmia (0.3[0.1-0.9] p = 0.043) were protective against lung involvement. Incidental imaging findings were found in 19% of patients, with a need for follow-up in 0.6%. Conclusion The prevalence of lung involvement was 54% in a predominantly paucisymptomatic population. Age >= 55 years and diabetes were risk factors for significant parenchymal lung involvement. Rhinitis and anosmia were protective against LDCT abnormalities.
%$ 050 ; 052