@article{fdi:010079985, title = {{V}ariation in the susceptibility of urban {A}edes mosquitoes infected with a densovirus}, author = {{P}errin, {A}. and {G}osselin-{G}renet, {A}. {S}. and {R}ossignol, {M}arie and {G}inibre, {C}arole and {S}cheid, {B}ethsab{\'e}e and {L}agneau, {C}. and {C}handre, {F}abrice and {B}aldet, {T}. and {O}gliastro, {M}. and {B}ouyer, {J}.}, editor = {}, language = {{ENG}}, abstract = {{U}rban {A}edes mosquitoes are vectors of many viruses affecting human health such as dengue, chikungunya and {Z}ika viruses. {I}nsecticide resistance and environmental toxicity risks hamper the effectiveness of chemical control against these mosquito vectors. {A}lternative control methods, such as the use of mosquito-specific entomopathogenic viruses should be explored. {N}umerous studies have focused on evaluating the potential of different densoviruses species as biological control agents. {H}owever, knowledge on the extent of inter- and intra-specific variations in the susceptibility of {A}edes mosquitoes to infection by different densoviruses remains insufficient. {I}n this study, we compared infection and mortality rates induced by the {A}edes albopictus densovirus 2 in different strains of {A}edes albopictus and {A}edes aegypti mosquitoes. {T}he two {A}edes species were different in terms of susceptibility to viral infection. {U}nder laboratory conditions, {A}edes albopictus densovirus 2 appeared more virulent for the different strains of {A}edes aegypti tested than for those of {A}edes albopictus. {I}n addition, we also found significant intra-specific variation in infection and mortality rates. {T}hus, although even if {A}edes albopictus densoviruses could be powerful biocontrol agents used in the management of urban {A}edes populations, our results also call into question the use of single viral isolate as biocontrol agents.}, keywords = {}, booktitle = {}, journal = {{S}cientific {R}eports - {N}ature}, volume = {10}, numero = {1}, pages = {18654 [8 ]}, ISSN = {2045-2322}, year = {2020}, URL = {https://www.documentation.ird.fr/hor/fdi:010079985}, }