@article{fdi:010079681,
  title = {{C}hemical composition and in vitro aryl hydrocarbon receptor-mediated activity of atmospheric particulate matter at an urban, agricultural and industrial site in {N}orth {A}frica ({B}izerte, {T}unisia)},
  author = {{B}arhoumi, {B}. and {T}edetti, {M}arc and {H}eimburger-{B}oavida, {L}. {E}. and {O}nrubia, {J}. {A}. {T}. and {D}ufour, {A}. and {D}oan, {Q}. {T}. and {B}outaleb, {S}. and {T}ouil, {S}. and {S}cippo, {M}. {L}.},
  editor = {},
  language = {{ENG}},
  abstract = {{A}s recognized risk factor to pose a health threat to humans and wildlife globally, atmospheric particulate matter ({PM}) were collected from a {N}orth {A}frican coastal city ({B}izerte, {T}unisia) for one year, and were characterized for their chemical compositions, including mercury ({H}g-{P}({M})), as well as organic contaminants (polycyclic aromatic hydrocarbons ({PAH}s), polychlorinated biphenyls ({PCB}s), organochlorine pesticides ({OCP}s)), organic carbon ({OC}) and organic nitrogen ({ON}), determined in a previous study. {T}hen, we applied an in vitro reporter gene assay ({DR}-{CALUX}) to detect and quantify the dioxin-like activity of {PM}-associated organic contaminants. {R}esults showed that average {H}g-{P}({M}) concentration over the entire sampling period was found to be 13.4 +/- 12 pg m(-3). {S}easonal variation in the {H}g-{PM} concentration was observed with lower values in spring and summer and higher values in winter and autumn due to the variation of meteorological conditions together with the emission sources. {P}rincipal component analysis suggested that fossil fuel combustion and a nearby cement factory were the dominant anthropogenic {H}gp {M} sources. {A}ryl hydrocarbon receptor ({A}h{R})-mediated activities were observed in all organic extracts of atmospheric {PM} from {B}izerte city (388.3-1543.6 fg m(-3)), and shows significant positive correlations with all {PM}-associated organic contaminants. {A} significant proportion of dioxin-like activity of {PM} was related to {PAH}s. {T}he dioxin-like activity followed the same trend as {PM}-associated organic contaminants, with higher dioxin-like activity in the cold season than in the warm season, indicating the advantage and utility of the use of bioassays in risk assessment of complex environmental samples.},
  keywords = {{A}ir pollution ; {O}rganic contaminants ; {M}ercury ; {DR}-{CALUX} ; {D}ioxin-like ; activity ; {TUNISIE} ; {BIZERTE} ; {AFRIQUE} {DU} {NORD}},
  booktitle = {},
  journal = {{C}hemosphere},
  volume = {258},
  numero = {},
  pages = {127312 [10 ]},
  ISSN = {0045-6535},
  year = {2020},
  DOI = {10.1016/j.chemosphere.2020.127312},
  URL = {https://www.documentation.ird.fr/hor/fdi:010079681},
}