@article{fdi:010079455,
  title = {{D}ietary bioaccumulation of persistent organic pollutants in the common sole {S}olea solea in the context of global change. {P}art 2 : {S}ensitivity of juvenile growth and contamination to toxicokinetic parameters uncertainty and environmental conditions variability in estuaries},
  author = {{M}ounier, {F}. and {L}oizeau, {V}. and {P}ecquerie, {L}aure and {D}rouineau, {H}. and {L}abadie, {P}. and {B}udzinski, {H}. and {L}obry, {J}.},
  editor = {},
  language = {{ENG}},
  abstract = {{T}he amount of potentially toxic chemicals in a fish depends on various environmental factors, such as temperature and feeding ecology, which can be affected by {G}lobal {C}hanges ({GC}). {T}he main objective of the present work was to study the relative influence of temperature, food quality and food availability on the growth and contamination of juveniles of common sole ({S}olea solea), a marine flatfish species known to be a relevant indicator of the nursery quality. {I}t focuses on two {P}ersistent {O}rganic {P}ollutants ({CB}153 and {L}-{PFOS}) of legacy and emerging concern, respectively. {T}o achieve this, we used a toxicokinetic ({TK}) model in which toxicant flows are mechanistically predicted using a bioenergetic model based on the {D}ynamic {E}nergy {B}udget ({DEB}) theory. {T}his modelling framework was applied to juvenile sole from the {G}ironde estuary ({SW} {F}rance) and allows accounting for the influence of environmental conditions on fish biological processes involved in toxicant fluxes. {T}o compare their respective influence on model predictions of age, length, and contamination at puberty, we included in a global sensitivity analysis: (1) environmental variability gathered from literature for this particular estuary and (2) {TK} parameters (i.e. assimilation efficiency {AE} and elimination rate (k) over dot(e)) variability and uncertainty gathered from literature about each contaminant but for different fish species and experimental conditions. {T}hen, model predictions were confronted to fish contamination measurements from the {G}ironde {E}stuary with different combinations of {TK} parameter values from literature. {R}esults highlighted a key role of diet composition on fish contamination and growth while water temperature only affected growth. {I}t stressed the need to focus on {GC} impact on benthic communities and their consequences on juvenile fish diet for future work on {GC} scenarios. {F}urthermore, for both chemical, the range of variability of {TK} parameters from experiments led to underestimated fish contaminations. {T}he best model fits were obtained using {TK} parameter values from model applications: from {M}ounier et al. for {CB}153 ({S}olea solea, experiment, {AE}= 0.8 and =0 d(-1)) and from de {V}os et al. (2008) for {PFOS} (food chain of the {W}estern {S}cheldt estuary, {T}he {N}etherlands, {AE} = 0.8 and (k) over dot(e)=0.8 10(-2) d(-1)).},
  keywords = {{G}ironde estuary ; {S}olea solea ; {DEB} model ; {TK} model ; {CB}153 ; {PFOS} ; sensitivity analysis ; {FRANCE} ; {GIRONDE} {ESTUAIRE}},
  booktitle = {},
  journal = {{E}cological {M}odelling},
  volume = {431},
  numero = {},
  pages = {art. 109196 [13]},
  ISSN = {0304-3800},
  year = {2020},
  DOI = {10.1016/j.ecolmodel.2020.109196},
  URL = {https://www.documentation.ird.fr/hor/fdi:010079455},
}