@article{fdi:010078587, title = {{C}omplete mitochondrial {DNA} sequence and amino acid analysis of the cytochrome {C} oxidase subunit {I} ({COI}) from {A}edes aegypti}, author = {{M}orlais, {I}sabelle and {S}everson, {D}.{W}.}, editor = {}, language = {{ENG}}, abstract = {{T}he complete sequence of the yellow fever mosquito, {A}edes aegypti, mitochondrial cytochrome c oxidase subunit 1 gene has been identified. {T}he nucleotide sequence codes for a 512 amino acid peptide. {T}he {A}e{COI} sequence is {A} + {T} rich (68.6%) and the codon usage is highly biased toward a preference for {A}- or {T}-ending triplets. {T}he {A}. aegypti {COI} peptide shows high homology, up to 93% identity, with several other insect sequences and a phylogenetic analysis indicates that the {A}. aegypti sequence is closely related to two other mosquito species, {A}nopheles gambiae and {A}. quadrimaculatus. {C}omparisons of the nucleotide sequence for four {A}. aegypti laboratory strains revealed single nucleotide polymorphisms, with 25 nucleotide sites showing {SNP}s between strains. {A}ll {SNP}s occurred as synonymous transitions such that the peptide sequence is conserved among {A}. aegypti strains. {RT}-{PCR} analysis showed that {COI} is expressed at similar levels in all developmental stages and tissues.}, keywords = {{MOUSTIQUE} ; {FIEVRE} {JAUNE} ; {VECTEUR} ; {CYTOGENETIQUE} ; {ADN}}, booktitle = {}, journal = {{DNA} {S}equences}, volume = {13}, numero = {2}, pages = {123--127}, ISSN = {1042-5179}, year = {2002}, DOI = {10.1080/10425170290030051}, URL = {https://www.documentation.ird.fr/hor/fdi:010078587}, }