@article{fdi:010077084, title = {{C}irculation of {T}oscana virus in a sample population of {C}orsica, {F}rance}, author = {{M}asse, {S}. and {A}yhan, {N}azli and {C}apai, {L}. and {B}osseur, {F}. and {L}amballerie, {X}. de and {C}harrel, {R}. and {F}alchi, {A}.}, editor = {}, language = {{ENG}}, abstract = {{S}andfly-borne phleboviruses pathogenic to humans, such as {T}oscana virus ({TOSV}) and {S}andfly {F}ever {S}icilian virus ({SFSV}), are endemic in the {M}editerranean region. {I}n {F}rance, several autochthonous cases of {TOSV} infection have been described, causing either meningitis or encephalitis. {T}he aim of the present study was to investigate the seroprevalence of {TOSV} and {SFSV} antibodies in a healthy population from {C}orsica. {I}n this cross-sectional study, participants were enrolled (i) from a medical staff at the {U}niversity of {C}orsica and (ii) from general practitioners of the {C}orsican {S}entinelles {N}etwork. {T}he seroprevalence study was based on a virus microneutralization assay. {A} total of 240 sera were tested. {A}ltogether, 54 sera (22.5%) were confirmed positive for {TOSV} antibodies, whereas none were positive for {SFSV} (0/240). {T}he residential district of participants was significantly associated with {TOSV} seropositivity (p value = 0.005). {T}he rate of the seropositivity against {TOSV} in our study suggests that the {C}orsican population is well exposed to the {TOSV}. {T}hese results encourage the implementation of a systematic surveillance system including entomological, microbiological, and medical aspects for the collection of better information on the diseases that are associated with phleboviruses in {C}orsica and beyond in the regions where these viruses are present.}, keywords = {{S}andfly {F}ever {S}icilian virus ; seroprevalence ; microneutralization ; meningitis ; arbovirus ; arthropod-borne virus ; {P}hlebovirus ; {P}henuiviridae ; {B}unyavirales ; sandfly ; {FRANCE} ; {CORSE} ; {ZONE} {MEDITERRANEENNE}}, booktitle = {}, journal = {{V}iruses}, volume = {11}, numero = {9}, pages = {art. 817 [8 p.]}, year = {2019}, DOI = {10.3390/v11090817}, URL = {https://www.documentation.ird.fr/hor/fdi:010077084}, }