@article{fdi:010077001,
  title = {{P}hylogenetic analysis revealed the cocirculation of four dengue virus serotypes in {S}outhern {T}hailand},
  author = {{H}amel, {R}odolphe and {S}urasombatpattana, {P}. and {W}ichit, {S}. and {D}auve, {A}. and {D}onato, {C}. and {P}ompon, {J}ulien and {V}ijaykrishna, {D}. and {L}i{\'e}geois, {F}lorian and {V}argas, {R}. {M}. and {L}uplertlop, {N}. and {M}iss{\'e}, {D}oroth{\'e}e},
  editor = {},
  language = {{ENG}},
  abstract = {{D}engue fever is caused by dengue viruses ({DENV}) from the {F}lavivirus genus and is the most prevalent arboviral disease. {DENV} exists in four immunogenically distinct and genetically-related serotypes ({DENV}-1 to 4), each subdivided in genotypes. {D}espite the endemicity of all four {DENV} serotypes in {T}hailand, no prior study has characterized the circulation of {DENV} in the southern provinces of the country. {T}o determine the genetic diversity of {DENV} circulating in {S}outhern {T}hailand in 2015 and 2016, we investigated 46 viruses from 182 patients' sera confirmed positive for {DENV} by serological and {N}ested {RT}-{PCR} tests. {O}ur dataset included 2 {DENV}-1, 20 {DENV}-2, 9 {DENV}-3 and 15 {DENV}-4. {P}hylogenetic analysis was performed on viral envelop sequences. {T}his revealed that part of the identified genotypes from {DENV}-1 and {DENV}-4 had been predominant in {A}sia (genotype {I} for both serotypes), while genotype {II} for {DENV}-4 and the {C}osmopolitan genotype {DENV}-2 were also circulating. {W}hereas {DENV}-3 genotype {II} had been predominantly detected in {S}outh {E}ast {A}sia during the previous decades, we found genotype {III} and genotype {I} in {S}outhern {T}hailand. {A}ll {DENV} genotype identified in this study were closely related to contemporary strains circulating in {S}outheast {A}sian countries, emphasizing the regional circulation of {DENV}. {T}hese results provide new insights into the co-circulation of all four {DENV} serotypes in {S}outhern {T}hailand, confirming the hyperendemicity of {DENV} in the region. {T}hese findings also suggest a new trend of dissemination for some {DENV} serotypes with a possible shift in genotype distribution; as recently observed in other {A}sian countries.},
  keywords = {{THAILANDE}},
  booktitle = {},
  journal = {{PL}o{S} {O}ne},
  volume = {14},
  numero = {8},
  pages = {art. e0221179 [16 ]},
  ISSN = {1932-6203},
  year = {2019},
  DOI = {10.1371/journal.pone.0221179},
  URL = {https://www.documentation.ird.fr/hor/fdi:010077001},
}