@article{fdi:010076701,
  title = {{S}porochartines {A}-{E}, a new family of natural products from the marine fungus {H}ypoxylon monticulosum isolated from a {S}phaerocladina sponge},
  author = {{L}eman-{L}oubi{\`e}re, {C}. and {L}e {G}off, {G}. and {D}ebitus, {C}{\'e}cile and {O}uazzani, {J}.},
  editor = {},
  language = {{ENG}},
  abstract = {{F}our new sporochartines {B}-{E} were isolated from the marine fungus {H}ypoxylon monticulosurn {CLL}-205, isolated from a sponge belonging to the {S}phaerocladina order and collected in {T}ahiti coast. {S}porochartine {A} (1), the first representative of this family was previously isolated from the same fungus. {T}he structures of sporochartines {B}-{E} were elucidated using 1{D} and 2{D} {NMR}, {HRMS} and {IR} data. {T}heir configurations were established according to {ROE} correlations and comparison with the absolute configuration of sporochartine {A} (1) previously obtained from {X}-ray analysis. {S}porochartines {A}-{D} (2-4) may be derived from endo {D}iels-{A}lderase type catalysis and sporochartine {E} (5) from an exo {D}iels-{A}lderase catalysis. {T}he spatial conformation of sporochartines drastically influences the results of the cytotoxic bioassay against {HCT}-116, {PC}-3, and {MCF}-7 human cancer cell lines.},
  keywords = {{TAHITI} ; {PACIFIQUE}},
  booktitle = {},
  journal = {{F}rontiers in {M}arine {S}cience},
  volume = {4},
  numero = {},
  pages = {art. 399},
  ISSN = {2296-7745},
  year = {2017},
  DOI = {10.3389/fmars.2017.00399},
  URL = {https://www.documentation.ird.fr/hor/fdi:010076701},
}