@article{fdi:010076290,
  title = {{U}terine balloon tamponade as an adjunct to misoprostol for the treatment of uncontrolled postpartum haemorrhage : a randomised controlled trial in {B}enin and {M}ali},
  author = {{D}umont, {A}lexandre and {B}odin, {C}. and {H}ounkpatin, {B}. and {P}opowski, {T}. and {T}raor{\'e}, {M}. and {P}errin, {R}. and {R}ozenberg, {P}.},
  editor = {},
  language = {{ENG}},
  abstract = {{O}bjective: {T}o assess the effectiveness of low-cost uterine tamponade as an adjunct to misoprostol for the treatment of uncontrolled postpartum haemorrhage ({PPH}) in low-resource settings. {D}esign {R}andomised controlled trial. {S}etting: {S}even healthcare facilities in {C}otonou, {B}enin and {B}amako, {M}ali. {P}opulation: {W}omen delivering vaginally who had clinically diagnosed {PPH} that was suspected to be due to uterine atony, who were unresponsive to oxytocin and who needed additional uterotonics. {M}ethods: {W}omen were randomly assigned to receive uterine balloon tamponade with a condom-catheter device or no tamponade; both groups were also given intrarectal or sublingual misoprostol. {M}ain outcome measure {P}roportion of women with invasive surgery or who died before hospital discharge. {R}esults: {T}he proportion of primary composite outcome did not differ significantly between the tamponade arm (16%; 9/57) and the standard second line treatment arm (7%; 4/59): relative risk 2.33 (95% {CI} 0.76 to 7.14, p= 0.238). {A} significantly increased proportion of women with tamponade and misoprostol versus misoprostol alone had total blood loss more than 1000 m{L}: relative risk 1.52 (95% {CI} 1.15 to 2.00, p= 0.01). {C}ase fatality rate was higher in the tamponade group (10%; 6/57) than in the control group (2%; 1/59) (p= 0.059).},
  keywords = {{FEMME} ; {SANTE} {PUBLIQUE} ; {GROSSESSE} ; {NAISSANCE} ; {ESSAI} {CLINIQUE} ; {SERVICE} {DE} {MATERNITE} ; {POPULATION} {URBAINE} ; {HEMORRAGIE} {POST} {PARTUM} ; {BENIN} ; {COTONOU} ; {MALI} ; {BAMAKO}},
  booktitle = {},
  journal = {{BMJ} {O}pen},
  volume = {7},
  numero = {9},
  pages = {e016590 [9 ]},
  ISSN = {2044-6055},
  year = {2017},
  DOI = {10.1136/bmjopen-2017-016590},
  URL = {https://www.documentation.ird.fr/hor/fdi:010076290},
}