@article{fdi:010076067, title = {{I}ntroducing risk inequality metrics in tuberculosis policy development}, author = {{G}omes, {M}. {G}. {M}. and {O}liveira, {J}. {F}. and {B}ertolde, {A}. and {A}yabina, {D}. and {N}guyen, {T}. {A}. and {M}aciel, {E}. {L}. and {D}uarte, {R}. and {N}guyen, {B}. {H}. and {S}hete, {P}. {B}. and {L}ienhardt, {C}hristian}, editor = {}, language = {{ENG}}, abstract = {{G}lobal stakeholders including the {W}orld {H}ealth {O}rganization rely on predictive models for developing strategies and setting targets for tuberculosis care and control programs. {F}ailure to account for variation in individual risk leads to substantial biases that impair data interpretation and policy decisions. {A}nticipated impediments to estimating heterogeneity for each parameter are discouraging despite considerable technical progress in recent years. {H}ere we identify acquisition of infection as the single process where heterogeneity most fundamentally impacts model outputs, due to selection imposed by dynamic forces of infection. {W}e introduce concrete metrics of risk inequality, demonstrate their utility in mathematical models, and pack the information into a risk inequality coefficient ({RIC}) which can be calculated and reported by national tuberculosis programs for use in policy development and modeling.}, keywords = {}, booktitle = {}, journal = {{N}ature {C}ommunications}, volume = {10}, numero = {}, pages = {art. 2480 [12 p.]}, ISSN = {2041-1723}, year = {2019}, DOI = {10.1038/s41467-019-10447-y}, URL = {https://www.documentation.ird.fr/hor/fdi:010076067}, }