Publications des scientifiques de l'IRD

Gomes M. G. M., Oliveira J. F., Bertolde A., Ayabina D., Nguyen T. A., Maciel E. L., Duarte R., Nguyen B. H., Shete P. B., Lienhardt Christian. (2019). Introducing risk inequality metrics in tuberculosis policy development. Nature Communications, 10, p. art. 2480 [12 p.]. ISSN 2041-1723.

Titre du document
Introducing risk inequality metrics in tuberculosis policy development
Année de publication
2019
Type de document
Article référencé dans le Web of Science WOS:000470248100012
Auteurs
Gomes M. G. M., Oliveira J. F., Bertolde A., Ayabina D., Nguyen T. A., Maciel E. L., Duarte R., Nguyen B. H., Shete P. B., Lienhardt Christian
Source
Nature Communications, 2019, 10, p. art. 2480 [12 p.] ISSN 2041-1723
Global stakeholders including the World Health Organization rely on predictive models for developing strategies and setting targets for tuberculosis care and control programs. Failure to account for variation in individual risk leads to substantial biases that impair data interpretation and policy decisions. Anticipated impediments to estimating heterogeneity for each parameter are discouraging despite considerable technical progress in recent years. Here we identify acquisition of infection as the single process where heterogeneity most fundamentally impacts model outputs, due to selection imposed by dynamic forces of infection. We introduce concrete metrics of risk inequality, demonstrate their utility in mathematical models, and pack the information into a risk inequality coefficient (RIC) which can be calculated and reported by national tuberculosis programs for use in policy development and modeling.
Plan de classement
Santé : généralités [050]
Localisation
Fonds IRD [F B010076067]
Identifiant IRD
fdi:010076067
Contact