@article{fdi:010075740, title = {{T}he oyster {C}rassostrea gigas, alpha new model against cancer}, author = {{C}orporeau, {C}. and {H}uvet, {A}. and {P}ichereau, {V}. and {D}elisle, {L}. and {Q}uere, {C}. and {D}ubreuil {T}ranchant, {C}hristine and {A}rtigaud, {S}. and {B}renner, {C}. and {C}unha-{D}e {P}adua, {M}. {M}. and {M}azure, {N}.}, editor = {}, language = {{FRE}}, abstract = {{T}he {W}arburg effect is one of the hallmarks of cancer cells in humans. {I}t is a true metabolic reprogramming to aerobic glycolysis, allowing cancer cells to meet their particular energy needs for growth, proliferation, and resistance to apoptosis, depending on the microenvironment they encounter within the tumor. {W}e have recently discovered that the {C}rassostrea gigas oyster can naturally reprogram its metabolism to the {W}arburg effect. {T}hus, the oyster becomes a new invertebrate model useful for cancer research. {D}ue to its lifestyle, the oyster {C}. gigas has special abilities to adapt its metabolism to the extreme changes in the environment in which it is located. {T}he oyster {C}. gigas is therefore a model of interest to study how the environment can control the {W}arburg effect under conditions that could not be explored in vertebrate model species.}, keywords = {}, booktitle = {}, journal = {{M} {S}-{M}edecine {S}ciences}, volume = {35}, numero = {5}, pages = {463--466}, ISSN = {0767-0974}, year = {2019}, DOI = {10.1051/medsci/2019079}, URL = {https://www.documentation.ird.fr/hor/fdi:010075740}, }