@article{fdi:010075642, title = {{S}ero-prevalence surveillance to predict vaccine-preventable disease outbreaks : a lesson from the 2014 measles epidemic in {N}orthern {V}ietnam}, author = {{C}hoisy, {M}arc and {T}ung, {T}. {S}. and {D}iep, {N}. {T}. {N}. and {H}ien, {N}. {T}. and {L}e, {M}. {Q}. and {T}hai, {P}. {Q}. and {D}uong, {T}. {N}. and {A}nh, {D}. {D}. and {H}orby, {P}. {W}. and {B}oni, {M}. {F}. and {B}ryant, {J}. and {L}ewycka, {S}. {O}. and {N}adjm, {B}. and van {D}oorn, {H}. {R}. and {W}ertheim, {H}. {F}. {L}.}, editor = {}, language = {{ENG}}, abstract = {{B}ackground. {D}uring the first half of 2014, a severe outbreak of measles occurred in northern {V}ietnam, causing 15 033 confirmed cases and 146 deaths. {M}ethods. {T}o evaluate the population-level seroprevalence of protection against measles in the period before the outbreak, we made use of an existing age-stratified serum bank, collected over the year before the outbreak, between {N}ovember 2012 and {D}ecember 2013, from 4 sites across the country ({H}anoi, {H}ue, {D}ak {L}ak, and {H}o {C}hi {M}inh {C}ity). {D}ata from the {UNICEF}'s {M}ultiple {I}ndicator {C}lustered {S}urveys ({MICS}), carried out in {V}ietnam during the first quarter of 2014, were used to assess the vaccine coverage in 6 ecological regions of {V}ietnam. {R}esults. {R}esults revealed a large discrepancy between levels of protection, as estimated from the serology and vaccine coverage estimated by {UNICEF}'s {MICS}. {V}ariation in seroprevalence across locations and age groups corresponded with reported numbers of measles cases, most of which were among the 0-2-year-old age group and in the northern part of the country. {C}onclusions. {O}ur study presents a strong case in favor of a serosurveillance sentinel network that could be used to proactively tune vaccination policies and other public health interventions.}, keywords = {measles ; seroprevalence ; vaccination ; {V}ietnam ; {VIET} {NAM}}, booktitle = {}, journal = {{O}pen {F}orum {I}nfectious {D}iseases}, volume = {6}, numero = {3}, pages = {art. ofz030 [7 p.]}, ISSN = {2328-8957}, year = {2019}, DOI = {10.1093/ofid/ofz030}, URL = {https://www.documentation.ird.fr/hor/fdi:010075642}, }