@article{fdi:010075618,
  title = {{M}olecular diagnosis of drug-resistant tuberculosis : a literature review},
  author = {{N}guyen, {T}. {N}. {A}. and {A}nton-{L}e {B}erra, {V}. and {B}anuls, {A}nne-{L}aure and {N}guyen, {T}. {V}. {A}.},
  editor = {},
  language = {{ENG}},
  abstract = {{D}rug-resistant tuberculosis is a global health problem that hinders the progress of tuberculosis eradication programs. {A}ccurate and early detection of drug-resistant tuberculosis is essential for effective patient care, for preventing tuberculosis spread, and for limiting the development of drug-resistant strains. {C}ulture-based drug susceptibility tests are the gold standard method for the detection of drug-resistant tuberculosis, but they are time-consuming and technically challenging, especially in low- and middle-income countries. {N}owadays, different nucleic acid-based assays that detect gene mutations associated with resistance to drugs used to treat tuberculosis are available. {T}hese tests vary in type and number of targets and in sensitivity and specificity. {I}n this review, we will describe the available molecular tests for drug-resistant tuberculosis detection and discuss their advantages and limitations.},
  keywords = {tuberculosis ; drug resistance ; diagnosis ; mutations ; molecular markers ; challenges ; {PAYS} {EN} {DEVELOPPEMENT}},
  booktitle = {},
  journal = {{F}rontiers in {M}icrobiology},
  volume = {10},
  numero = {},
  pages = {art. 794 [12 ]},
  ISSN = {1664-302{X}},
  year = {2019},
  DOI = {10.3389/fmicb.2019.00794},
  URL = {https://www.documentation.ird.fr/hor/fdi:010075618},
}