@article{fdi:010075615,
  title = {{P}otential herd protection against {P}lasmodium falciparum infections conferred by mass antimalarial drug administrations},
  author = {{P}arker, {D}. {M}. and {T}un, {S}. {T}. {T}. and {W}hite, {L}. {J}. and {K}ajeechiwa, {L}. and {T}hwin, {M}. {M}. and {L}andier, {J}ordi and {C}haumeau, {V}. and {C}orbel, {V}incent and {D}ondorp, {A}. {M}. and von {S}eidlein, {L}. and {W}hite, {N}. {J}. and {M}endez, {R}. {J}. and {N}osten, {F}.},
  editor = {},
  language = {{ENG}},
  abstract = {{T}he global malaria burden has decreased over the last decade and many nations are attempting elimination. {A}symptomatic malaria infections are not normally diagnosed or treated, posing a major hurdle for elimination efforts. {O}ne solution to this problem is mass drug administration ({MDA}), with success depending on adequate population participation. {H}ere, we present a detailed spatial and temporal analysis of malaria episodes and asymptomatic infections in four villages undergoing {MDA} in {M}yanmar. {I}n this study, individuals from neighborhoods with low {MDA} adherence had 2.85 times the odds of having a malaria episode post-{MDA} in comparison to those from high adherence neighborhoods, regardless of individual participation, suggesting a herd effect. {H}igh mosquito biting rates, living in a house with someone else with malaria, or having an asymptomatic malaria infection were also predictors of clinical episodes. {S}patial clustering of non-adherence to {MDA}, even in villages with high overall participation, may frustrate elimination efforts.},
  keywords = {{MYANMAR}},
  booktitle = {},
  journal = {e-{L}ife},
  volume = {8},
  numero = {},
  pages = {e41023 [22 p.]},
  ISSN = {2050-084{X}},
  year = {2019},
  DOI = {10.7554/e{L}ife.41023},
  URL = {https://www.documentation.ird.fr/hor/fdi:010075615},
}