Trung N. V., Hoi L., Dien V. M., Huong D. T., Hoa T. M., Lien V. N., Luan V., Lewycka S. O., Choisy Marc, Bryant J. E., Nadjm B., Van Doorn H. R., Richards A. L., Van Kinh N. (2019). Clinical manifestations and molecular diagnosis of scrub typhus and murine typhus Vietnam, 2015-2017. Emerging Infectious Diseases, 25 (4), p. 633-641. ISSN 1080-6040.
Titre du document
Clinical manifestations and molecular diagnosis of scrub typhus and murine typhus Vietnam, 2015-2017
Année de publication
2019
Auteurs
Trung N. V., Hoi L., Dien V. M., Huong D. T., Hoa T. M., Lien V. N., Luan V., Lewycka S. O., Choisy Marc, Bryant J. E., Nadjm B., Van Doorn H. R., Richards A. L., Van Kinh N.
Source
Emerging Infectious Diseases, 2019,
25 (4), p. 633-641 ISSN 1080-6040
Rickettsioses are endemic to Vietnam; however, only a limited number of clinical studies have been performed on these vectorborne bacteria. We conducted a prospective hospital-based study at 2 national referral hospitals in Hanoi to describe the clinical characteristics of scrub typhus and murine typhus in northern Vietnam and to assess the diagnostic applicability of quantitative real-time PCR assays to diagnose rickettsia' diseases. We enrolled 302 patients with acute undifferentiated fever and clinically suspected rickettsiosis during March 2015-March 2017. We used a standardized case report form to collect clinical information and laboratory results at the time of admission and during treatment. We confirmed scrub typhus in 103 (34.1%) patients and murine typhus in 12 (3.3%) patients. These results highlight the need for increased emphasis on training for healthcare providers for earlier recognition, prevention, and treatment of rickettsial diseases in Vietnam.
Plan de classement
Santé : généralités [050]
;
Entomologie médicale / Parasitologie / Virologie [052]
;
Sciences du monde animal [080]
Description Géographique
VIET NAM
Localisation
Fonds IRD [F B010075483]
Identifiant IRD
fdi:010075483
