@article{fdi:010075342,
  title = {{E}valuating effectiveness of mass and continuous long-lasting insecticidal net distributions over time in {M}adagascar : a sentinel surveillance based epidemiological study},
  author = {{G}irond, {F}. and {M}adec, {Y}. and {K}esteman, {T}. and {R}andrainarivelojosia, {M}. and {R}andremanana, {R}. and {R}andriamampionona, {L}. and {R}andrainasolo, {L}. and {R}atsitorahina, {M}. and {H}erbreteau, {V}incent and {H}edje, {J}. and {R}ogier, {C}. and {P}iola, {P}.},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ackground: {T}he reduction of global malaria burden over the past 15 years is much attributed to the expansion of mass distribution campaigns ({MDC}s) of long-lasting insecticidal nets ({LLIN}). {I}n {M}adagascar, two {LLIN} {MDC}s were implemented and one district also benefited from a community-based continuous distribution ({CB}-{CD}). {M}alaria incidence dropped but eventually rebounded after a decade.  {M}ethods: {D}ata from a sentinel surveillance network over the 2009-2015 period was analyzed. {A}lerts were defined as weekly number of malaria cases exceeding the 90th percentile value for three consecutive weeks. {S}tatistical analyses assessed the temporal relationship between {LLIN} {MDC}s and (i) number of malaria cases and (ii) malaria alerts detected, and (iii) the effect of a combination of {MDC}s and a {CB}-{CD} in {T}oamasina {D}istrict.  {F}indings: {A}nalyses showed an increase of 13.6 points and 21.4 points in the percentile value of weekly malaria cases during the second and the third year following the {MDC} of {LLIN}s respectively. {T}he percentage of alert-free sentinel sites was 98.2% during the first year after {LLIN} {MDC}, 56.7% during the second year and 31.5% during the third year. {T}he number of weekly malaria cases decreased by 14% during the {CB}-{CD} in {T}oamasina {D}istrict. {I}n contrast, sites without continuous distribution had a 12% increase of malaria cases. {I}nterpretation: {T}hese findings support the malaria-preventive effectiveness of {MDC}s in {M}adagascar but highlight their limited duration when not followed by continuous distribution. {T}he resulting policy implications are crucial to sustain reductions in malaria burden in high transmission settings.},
  keywords = {{PALUDISME} ; {EPIDEMIOLOGIE} ; {SURVEILLANCE} ; {PREVENTION} {SANITAIRE} ; {INSECTICIDE} {CHIMIQUE} ; {ANALYSE} {STATISTIQUE} ; {ANALYSE} {DIACHRONIQUE} ; {MADAGASCAR} ; {TOAMASINA}},
  booktitle = {},
  journal = {{EC}linical{M}edicine},
  volume = {1},
  numero = {},
  pages = {62--69},
  ISSN = {2589-5370},
  year = {2018},
  DOI = {10.1016/j.eclinm.2018.07.003},
  URL = {https://www.documentation.ird.fr/hor/fdi:010075342},
}