Publications des scientifiques de l'IRD

Girond F., Madec Y., Kesteman T., Randrainarivelojosia M., Randremanana R., Randriamampionona L., Randrainasolo L., Ratsitorahina M., Herbreteau Vincent, Hedje J., Rogier C., Piola P. (2018). Evaluating effectiveness of mass and continuous long-lasting insecticidal net distributions over time in Madagascar : a sentinel surveillance based epidemiological study. EClinicalMedicine, 1, p. 62-69. ISSN 2589-5370.

Titre du document
Evaluating effectiveness of mass and continuous long-lasting insecticidal net distributions over time in Madagascar : a sentinel surveillance based epidemiological study
Année de publication
2018
Type de document
Article
Auteurs
Girond F., Madec Y., Kesteman T., Randrainarivelojosia M., Randremanana R., Randriamampionona L., Randrainasolo L., Ratsitorahina M., Herbreteau Vincent, Hedje J., Rogier C., Piola P.
Source
EClinicalMedicine, 2018, 1, p. 62-69 ISSN 2589-5370
Background: The reduction of global malaria burden over the past 15 years is much attributed to the expansion of mass distribution campaigns (MDCs) of long-lasting insecticidal nets (LLIN). In Madagascar, two LLIN MDCs were implemented and one district also benefited from a community-based continuous distribution (CB-CD). Malaria incidence dropped but eventually rebounded after a decade. Methods: Data from a sentinel surveillance network over the 2009-2015 period was analyzed. Alerts were defined as weekly number of malaria cases exceeding the 90th percentile value for three consecutive weeks. Statistical analyses assessed the temporal relationship between LLIN MDCs and (i) number of malaria cases and (ii) malaria alerts detected, and (iii) the effect of a combination of MDCs and a CB-CD in Toamasina District. Findings: Analyses showed an increase of 13.6 points and 21.4 points in the percentile value of weekly malaria cases during the second and the third year following the MDC of LLINs respectively. The percentage of alert-free sentinel sites was 98.2% during the first year after LLIN MDC, 56.7% during the second year and 31.5% during the third year. The number of weekly malaria cases decreased by 14% during the CB-CD in Toamasina District. In contrast, sites without continuous distribution had a 12% increase of malaria cases. Interpretation: These findings support the malaria-preventive effectiveness of MDCs in Madagascar but highlight their limited duration when not followed by continuous distribution. The resulting policy implications are crucial to sustain reductions in malaria burden in high transmission settings.
Plan de classement
Etudes régionales [050ETUREG] ; Epidémiologie du paludisme [052ANOPAL03]
Descripteurs
PALUDISME ; EPIDEMIOLOGIE ; SURVEILLANCE ; PREVENTION SANITAIRE ; INSECTICIDE CHIMIQUE ; ANALYSE STATISTIQUE ; ANALYSE DIACHRONIQUE
Description Géographique
MADAGASCAR ; TOAMASINA
Localisation
Fonds IRD [F B010075342]
Identifiant IRD
fdi:010075342
Contact