@article{fdi:010074862,
  title = {{C}ombination of {ELISA} screening and seroneutralisation tests to expedite {Z}ika virus seroprevalence studies [+ {C}orrection 2019, vol 16, 1 p.]},
  author = {{N}urtop, {E}. and {V}illarroel, {P}. {M}. {S}. and {P}astorino, {B}. and {N}inove, {L}. and {D}rexler, {J}. {F}. and {R}oca, {Y}. and {G}ake, {B}. and {D}ubot {P}{\'e}r{\`e}s, {A}udrey and {G}rard, {G}. and {P}eyrefitte, {C}. and {P}riet, {S}. and {L}amballerie, {X}. de and {G}allian, {P}.},
  editor = {},
  language = {{ENG}},
  abstract = {{H}ere we propose a strategy allowing implementing efficient and practicable large-scale seroepidemiological studies for {Z}ika {V}irus ({ZIKV}). {I}t combines screening by a commercial {NS}1 protein-based {Z}ika {I}g{G} {ELISA}, and confirmation by a cytopathic effect-based virus neutralization test ({CPE}-based {VNT}). {I}n post-epidemic samples from {M}artinique {I}sland blood donors (a population with a dengue seroprevalence above 90%), this strategy allowed reaching specificity and sensitivity values over 98%. {T}he {CPE}-based {VNT} consists of recording {CPE} directly under the optical microscope, which is easy to identify with {ZIKV} strain {H}/{PF}/2013 at day 5 pi. {O}verall, considered that {CPE}-based {VNT} is cost effective and widely automatable, the {NS}1 protein-based {Z}ika {I}g{G} {ELISA}+{CPE}-based {VNT} combination strategy represents a convenient tool to expedite {ZIKV} seroprevalence studies.},
  keywords = {{Z}ika virus ; {S}eroepidemiology ; {V}irus neutralization test ; {MARTINIQUE} ; {GUADELOUPE} ; {FRANCE} ; {CAMEROUN}},
  booktitle = {},
  journal = {{V}irology {J}ournal},
  volume = {15},
  numero = {},
  pages = {art. 192 [6 + correction]},
  ISSN = {1743-422{X}},
  year = {2018},
  DOI = {10.1186/s12985-018-1105-5},
  URL = {https://www.documentation.ird.fr/hor/fdi:010074862},
}