Horizon / Plein textes La base de ressources documentaires de l'IRD

IRD

 

Publications des scientifiques de l'IRD

Bassene Hubert, Niang E. A., Fenollar F., Dipankar B., Doucouré Souleymane, Ali E., Michelle C., Raoult D., Sokhna Cheikh, Mediannikov Oleg. (2018). 16S metagenomic comparison of Plasmodium falciparum-infected and noninfected Anopheles gambiae and Anopheles funestus microbiota from Senegal. American Journal of Tropical Medicine and Hygiene, 99 (6), 1489-1498. ISSN 0002-9637

Accès réservé (Intranet IRD) Demander le PDF

Lien direct chez l'éditeur doi:10.4269/ajtmh.18-0263

Titre
16S metagenomic comparison of Plasmodium falciparum-infected and noninfected Anopheles gambiae and Anopheles funestus microbiota from Senegal
Année de publication2018
Type de documentArticle référencé dans le Web of Science WOS:000452400500023
AuteursBassene Hubert, Niang E. A., Fenollar F., Dipankar B., Doucouré Souleymane, Ali E., Michelle C., Raoult D., Sokhna Cheikh, Mediannikov Oleg.
SourceAmerican Journal of Tropical Medicine and Hygiene, 2018, 99 (6), p. 1489-1498. ISSN 0002-9637
RésuméIn the context of the pre-elimination of malaria, biological control may provide an alternative or additional tool to current malaria control strategies. During their various stages of development, mosquitoes undergo subsequent changes in their associated microbiota, depending on their environment and nutritional status. Although Anopheles gambiae s.l. and Anopheles funestus are the two major malaria vectors in Senegal, the composition of their microbiota is not yet well known. In this study, we explored the microbiota of mosquitoes naturally infected or not by Plasmodium falciparum (Pf) using the 16S ribosomal RNA gene-based bacterial metagenomic approach. In both vector species, the microbiota was more diverse in Pf-infected samples than in the noninfected ones, although the total number of reads appeared to be higher in noninfected mosquitoes. Overall, the microbiota was different between the two vector species. Noteworthy, the bacterial microbiota was significantly different between Pf-positive and Pf-negative groups whatever the species, but was similar between individuals of the same infection status within a species. Overall, the phylum of Proteobacteria was the most predominant in both species, with bacteria of the genus Burkholderia outweighing the others in noninfected vectors. The presence of some specific bacterial species such as Asaia bogorensis, Enterobacter cloacae, Burkholderia fungorum, and Burkholderia cepacia was also observed in Pf-free samples only. These preliminary observations pave the way for further characterization of the mosquito microbiota to select promising bacterial candidates for potential use in an innovative approach to controlling malaria and overcoming the challenges to achieving a malaria-free world.
Plan de classementEntomologie médicale / Parasitologie / Virologie [052] ; Biotechnologies [084]
Descr. géo.SENEGAL
LocalisationFonds IRD [F B010074527]
Identifiant IRDfdi:010074527
Lien permanenthttp://www.documentation.ird.fr/hor/fdi:010074527

Export des données

Disponibilité des documents

Télechargment fichier PDF téléchargeable

Lien sur le Web lien chez l'éditeur

Accès réservé en accès réservé

HAL en libre accès sur HAL


Accès aux documents originaux :

Le FDI est labellisé CollEx

Accès direct

Bureau du chercheur

Site de la documentation

Espace intranet IST (accès réservé)

Suivi des publications IRD (accès réservé)

Mentions légales

Services Horizon

Poser une question

Consulter l'aide en ligne

Déposer une publication (accès réservé)

S'abonner au flux RSS

Voir les tableaux chronologiques et thématiques

Centres de documentation

Bondy

Montpellier (centre IRD)

Montpellier (MSE)

Cayenne

Nouméa

Papeete

Abidjan

Dakar

Niamey

Ouagadougou

Tunis

La Paz

Quito