@article{fdi:010074501, title = {{S}ystematic review of indoor residual spray efficacy and effectiveness against {P}lasmodium falciparum in {A}frica}, author = {{S}herrard-{S}mith, {E}. and {G}riffin, {J}. {T}. and {W}inskill, {P}. and {C}orbel, {V}incent and {P}ennetier, {C}{\'e}dric and {D}jenontin, {A}. and {M}oore, {S}. and {R}ichardson, {J}. {H}. and {M}uller, {P}. and {E}di, {C}. and {P}rotopopoff, {N}. and {O}xborough, {R}. and {A}gossa, {F}. and {N}'{G}uessan, {R}. and {R}owland, {M}. and {C}hurcher, {T}. {S}.}, editor = {}, language = {{ENG}}, abstract = {{I}ndoor residual spraying ({IRS}) is an important part of malaria control. {T}here is a growing list of insecticide classes; pyrethroids remain the principal insecticide used in bednets but recently, novel non-pyrethroid {IRS} products, with contrasting impacts, have been introduced. {T}here is an urgent need to better assess product efficacy to help decision makers choose effective and relevant tools for mosquito control. {H}ere we use experimental hut trial data to characterise the entomological efficacy of widely-used, novel {IRS} insecticides. {W}e quantify their impact against pyrethroid-resistant mosquitoes and use a {P}lasmodium falciparum transmission model to predict the public health impact of different {IRS} insecticides. {W}e report that long-lasting {IRS} formulations substantially reduce malaria, though their benefit over cheaper, shorter-lived formulations depends on local factors including bednet use, seasonality, endemicity and pyrethroid resistance status of local mosquito populations. {W}e provide a framework to help decision makers evaluate {IRS} product effectiveness.}, keywords = {{BENIN} ; {COTE} {D}'{IVOIRE} ; {BURKINA} {FASO} ; {TANZANIE}}, booktitle = {}, journal = {{N}ature {C}ommunications}, volume = {9}, numero = {}, pages = {art. 4982 [13 p.]}, ISSN = {2041-1723}, year = {2018}, DOI = {10.1038/s41467-018-07357-w}, URL = {https://www.documentation.ird.fr/hor/fdi:010074501}, }