@article{fdi:010073768,
  title = {{A}llelic variation for broad-spectrum resistance and susceptibility to bacterial pathogens identified in a rice {MAGIC} population},
  author = {{B}ossa-{C}astro, {A}. {M}. and {T}ekete, {C}. and {R}aghavan, {C}. and {D}elorean, {E}. {E}. and {D}ereeper, {A}lexis and {D}agno, {K}. and {K}oita, {O}. and {M}osquera, {G}. and {L}eung, {H}. and {V}erdier, {V}al{\'e}rie and {L}each, {J}. {E}.},
  editor = {},
  language = {{ENG}},
  abstract = {{Q}uantitative trait loci ({QTL}) that confer broad-spectrum resistance ({BSR}), or resistance that is effective against multiple and diverse plant pathogens, have been elusive targets of crop breeding programmes. {M}ultiparent advanced generation intercross ({MAGIC}) populations, with their diverse genetic composition and high levels of recombination, are potential resources for the identification of {QTL} for {BSR}. {I}n this study, a rice {MAGIC} population was used to map {QTL} conferring {BSR} to two major rice diseases, bacterial leaf streak ({BLS}) and bacterial blight ({BB}), caused by {X}anthomonas oryzae pathovars (pv.) oryzicola ({X}oc) and oryzae ({X}oo), respectively. {C}ontrolling these diseases is particularly important in sub-{S}aharan {A}frica, where no sources of {BSR} are currently available in deployed varieties. {T}he {MAGIC} founders and lines were genotyped by sequencing and phenotyped in the greenhouse and field by inoculation with multiple strains of {X}oc and {X}oo. {A} combination of genomewide association studies ({GWAS}) and interval mapping analyses revealed 11 {BSR} {QTL}, effective against both diseases, and three pathovar-specific {QTL}. {T}he most promising {BSR} {QTL} (q{XO}-2-1, q{XO}-4-1 and q{XO}-11-2) conferred resistance to more than nine {X}oc and {X}oo strains. {GWAS} detected 369 significant {SNP} markers with distinguishable phenotypic effects, allowing the identification of alleles conferring disease resistance and susceptibility. {T}he {BSR} and susceptibility {QTL} will improve our understanding of the mechanisms of both resistance and susceptibility in the long term and will be immediately useful resources for rice breeding programmes.},
  keywords = {broad-spectrum resistance ; multiparent advanced generation intercross ; {X}anthomonas oryzae ; {A}frica ; bacterial leaf streak ; bacterial blight ; {AFRIQUE} {SUBSAHARIENNE}},
  booktitle = {},
  journal = {{P}lant {B}iotechnology {J}ournal},
  volume = {16},
  numero = {9},
  pages = {1559--1568},
  ISSN = {1467-7644},
  year = {2018},
  DOI = {10.1111/pbi.12895},
  URL = {https://www.documentation.ird.fr/hor/fdi:010073768},
}