@article{fdi:010073741,
  title = {{Z}ika virus outbreak in the {P}acific : vector competence of regional vectors},
  author = {{C}alvez, {E}. and {M}ousson, {L}. and {V}azeille, {M}. and {O}'{C}onnor, {O}. and {C}ao-{L}ormeau, {V}. {M}. and {M}athieu-{D}aud{\'e}, {F}ran{\c{c}}oise and {P}ocquet, {N}. and {F}ailloux, {A}. {B}. and {D}upont-{R}ouzeyrol, {M}.},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ackground {I}n 2013, {Z}ika virus ({ZIKV}) emerged in {F}rench {P}olynesia and spread through the {P}acific region between 2013 and 2017. {S}everal potential {A}edes mosquitoes may have contributed to the {ZIKV} transmission including {A}edes aegypti, the main arbovirus vector in the region, and {A}edes polynesiensis, vector of lymphatic filariasis and secondary vector of dengue virus. {T}he aim of this study was to analyze the ability of these two {P}acific vectors to transmit {ZIKV} at a regional scale, through the evaluation and comparison of the vector competence of wild {A}e. aegypti and {A}e. polynesiensis populations from different {P}acific islands for a {ZIKV} strain which circulated in this region during the 2013-2017 outbreak. {M}ethodology/principal findings {F}ield {A}e. aegypti (three populations) and {A}e. polynesiensis (two populations) from the {P}acific region were collected for this study. {F}emale mosquitoes were orally exposed to {ZIKV} (10 7 {TCID}50/m{L}) isolated in the region in 2014. {A}t 6, 9, 14 and 21 days post-infection, mosquito bodies (thorax and abdomen), heads and saliva were analyzed to measure infection, dissemination, transmission rates and transmission efficiency, respectively. {A}ccording to our results, {ZIKV} infection rates were heterogeneous between the {A}e. aegypti populations, but the dissemination rates were moderate and more homogenous between these populations. {F}or {A}e. polynesiensis, infection rates were less heterogeneous between the two populations tested. {T}he transmission rate and efficiency results revealed a low vector competence for {ZIKV} of the different {A}edes vector populations under study. {C}onclusion/significance {O}ur results indicated a low {ZIKV} transmission by {A}e. aegypti and {A}e. polynesiensis tested from the {P}acific region. {T}hese results were unexpected and suggest the importance of other factors especially the vector density, the mosquito lifespan or the large immunologically naive fraction of the population that may have contributed to the rapid spread of the {ZIKV} in the {P}acific region during the 2013-2017 outbreak.},
  keywords = {{PACIFIQUE} ; {POLYNESIE} {FRANCAISE} ; {NOUVELLE} {CALEDONIE} ; {WALLIS} {ET} {FUTUNA} ; {SAMOA}},
  booktitle = {},
  journal = {{PL}o{S} {N}eglected {T}ropical {D}iseases},
  volume = {12},
  numero = {7},
  pages = {e0006637 [12 p.]},
  ISSN = {1935-2735},
  year = {2018},
  DOI = {10.1371/journal.pntd.0006637},
  URL = {https://www.documentation.ird.fr/hor/fdi:010073741},
}