@article{fdi:010073736,
  title = {{E}fficacy of {I}nterceptor ({R}) {G}2, a new long-lasting insecticidal net against wild pyrethroid-resistant {A}nopheles gambiae s.s. from {C}ote d'{I}voire : a semi-field trial},
  author = {{C}amara, {S}. and {A}lou, {L}. {P}. {A}. and {K}offi, {A}. {A}. and {C}legban, {Y}. {C}. {M}. and {K}abran, {J}. {P}. and {K}offi, {F}. {M}. and {K}offi, {K}. and {P}ennetier, {C}{\'e}dric},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ackground: {T}he widespread insecticide resistance in malaria vector populations is a serious threat to the efficacy of vector control tools. {A}s a result, the {W}orld {H}ealth {O}rganization ({WHO}) supports the development of alternative tools that combine several insecticides with the aim of improving vector control and the management of insecticide resistance. {I}n the present study, a long-lasting insecticidal net treated with a mixture of chlorfenapyr and alphacypermethrin was evaluated against wild pyrethroid-resistant {A}nopheles gambiae s.s in {M}'be, {C}ote d'{I}voire. {C}enters for {D}isease {C}ontrol and {P}revention ({CDC}) bottle tests were carried out with resistant {A}n. gambiae s.s. of {M}'be and the susceptible strain, to assess the resistance level to chlorfenapyr and alphacypermethrin. {R}esults: {CDC} bottle bioassays revealed a high level of resistance of {A}n. gambiae s.s. population from {M}'be to alphacypermethrin, whereas they revealed low resistance to chlorfenapyr. {I}n experimental huts, {I}nterceptor ({R}) {G}2 that was unwashed or washed 20 times killed 87% and 82% of {A}n. gambiae s.s., respectively, whereas {I}nterceptor ({R}) {LN} that was either unwashed or washed 20 times killed only about 10% of the mosquitoes. {T}he blood-feeding inhibition induced by {I}nterceptor ({R}) was not significantly different compared to untreated nets, whereas {I}nterceptor ({R}) {G}2 that was unwashed or washed 20 times induced 42% and 34% inhibition of blood-feeding, respectively. {C}onclusion: {I}nterceptor ({R}) {G}2 met the {WHOPES} criteria to undergo a phase {III} study. {I}nvestigation of its efficacy at a community level and the conduct of randomized controlled trials dealing with epidemiological outputs are warranted in order to study the potential of {I}nterceptor ({R}) {G}2 to better protect communities.},
  keywords = {{M}alaria ; {A}nopheles gambiae s.s. ; insecticides ; chlorfenapyr ; pyrethroid ; resistance ; {COTE} {D}'{IVOIRE}},
  booktitle = {},
  journal = {{P}arasite},
  volume = {25},
  numero = {},
  pages = {art. 42 [11 p.]},
  ISSN = {1252-607{X}},
  year = {2018},
  DOI = {10.1051/parasite/2018042},
  URL = {https://www.documentation.ird.fr/hor/fdi:010073736},
}