@article{fdi:010073648,
  title = {{E}ffect of stirring on growth and cellulolytic enzymes production by {T}richoderma harzianum in a novel bench-scale solid-state fermentation bioreactor},
  author = {{L}opez-{R}amirez, {N}. and {V}olke-{S}epulveda, {T}. and {P}erraud {G}aime, {I}sabelle and {S}aucedo-{C}astaneda, {G}. and {F}avela-{T}orres, {E}.},
  editor = {},
  language = {{ENG}},
  abstract = {{A} novel bench-scale stirred bioreactor for solid-state fermentation was used to determine the effect of the stirring rate on growth and enzymes production by {T}richoderma harzianum {PBLA}. {L}ab-scale static tubular bioreactors were first used to assess the effect of bioreactor diameter on heat accumulation, growth, and production of cellulases and xylanases. {T}he increased diameters (1.8-4.2 cm) led to increases in temperature up to 36 degrees {C} (at a rate of 1.08 degrees {C}/cm), which negatively affected the growth and enzyme production. {A}fterward, in the bench-scale bioreactor operated at rates up to 3.0 rpm, maximum xylanases production (107 +/- 0.3 {U}/g dm) was attained at rates of 0.5 and 1.0 rpm, reaching a maximum of 34 +/- 0.3 degrees {C}. {C}ellulases production was reduced (up to 79%) due to stirring. {T}herefore, the production of xylanases by {T}. harzianum can be performed in this cross-flow stirred {SSF} bioreactor at rates up to 1.0 rpm, avoiding heat accumulation and damage on metabolic activity.},
  keywords = {{S}olid-state fermentation ; {S}tirred bioreactor ; {R}espirometry ; {T}richoderma harzianum ; {C}ellulases ; {X}ylanases},
  booktitle = {},
  journal = {{B}ioresource {T}echnology},
  volume = {265},
  numero = {},
  pages = {291--298},
  ISSN = {0960-8524},
  year = {2018},
  DOI = {10.1016/j.biortech.2018.06.015},
  URL = {https://www.documentation.ird.fr/hor/fdi:010073648},
}