@article{fdi:010073231,
  title = {{W}hat does the future hold for yellow fever virus ? ({I})},
  author = {{K}litting, {R}. and {G}ould, {E}. {A}. and {P}aupy, {C}hristophe and de {L}amballerie, {X}.},
  editor = {},
  language = {{ENG}},
  abstract = {{T}he recent resurgence of yellow fever virus ({YFV}) activity in the tropical regions of {A}frica and {S}outh {A}merica has sparked renewed interest in this infamous arboviral disease. {Y}ellow fever virus had been a human plague for centuries prior to the identification of its urban transmission vector, the {A}edes ({S}tegomyia) aegypti ({L}innaeus) mosquito species, and the development of an efficient live-attenuated vaccine, the {YF}-17{D} strain. {T}he combination of vector-control measures and vaccination campaigns drastically reduced {YFV} incidence in humans on many occasions, but the virus never ceased to circulate in the forest, through its sylvatic invertebrate vector(s) and vertebrate host(s). {O}utbreaks recently reported in {C}entral {A}frica (2015-2016) and {B}razil (since late 2016), reached considerable proportions in terms of spatial distribution and total numbers of cases, with multiple exports, including to {C}hina. {I}n turn, questions about the likeliness of occurrence of large urban {YFV} outbreaks in the {A}mericas or of a successful import of {YFV} to {A}sia are currently resurfacing. {T}his two-part review describes the current state of knowledge and gaps regarding the molecular biology and transmission dynamics of {YFV}, along with an overview of the tools that can be used to manage the disease at individual, local and global levels.},
  keywords = {yellow fever virus ; flavivirus ; vector-borne transmission ; emergence ; {AFRIQUE} {SUBSAHARIENNE} ; {AMERIQUE} {DU} {SUD}},
  booktitle = {},
  journal = {{G}enes},
  volume = {9},
  numero = {6},
  pages = {291 [27 ]},
  ISSN = {2073-4425},
  year = {2018},
  DOI = {10.3390/genes9060291},
  URL = {https://www.documentation.ird.fr/hor/fdi:010073231},
}