@article{fdi:010073221,
  title = {{A}n apportionment method for the oxidative potential of atmospheric particulate matter sources : application to a one-year study in {C}hamonix, {F}rance},
  author = {{W}eber, {S}. and {U}zu, {G}a{\¨e}lle and {C}alas, {A}. and {C}hevrier, {F}. and {B}esombes, {J}. {L}. and {C}harron, {A}. and {S}alameh, {D}. and {J}ezek, {I}. and {M}ocnik, {G}. and {J}affrezo, {J}. {L}.},
  editor = {},
  language = {{ENG}},
  abstract = {{I}nhaled aerosolized particulate matter ({PM}) induces cellular oxidative stress in vivo, leading to adverse health outcomes. {T}he oxidative potential ({OP}) of {PM} appears to be a more relevant proxy of the health impact of the aerosol rather than the total mass concentration. {H}owever, the relative contributions of the aerosol sources to the {OP} are still poorly known. {I}n order to better quantify the impact of different {PM} sources, we sampled aerosols in a {F}rench city for one year (2014, 115 samples). {A} coupled analysis with detailed chemical speciation (more than 100 species, including organic and carbonaceous compounds, ions, metals and aethalometer measurements) and two {OP} assays (ascorbic acid, {AA}, and dithiothreitiol, {DTT}) in a simulated lung fluid ({SLF}) were performed in these samples. {W}e present in this study a statistical framework using a coupled approach with positive matrix factorization ({PMF}) and multiple linear regression to attribute a redox-activity to {PM} sources. {O}ur results highlight the importance of the biomass burning and vehicular sources to explain the observed {OP} for both assays. {I}n general, we see a different contribution of the sources when considering the {OP} {AA}, {OP} {DTT} or the mass of the {PM}10. {M}oreover, significant differences are observed between the {DTT} and {AA} tests which emphasized chemical specificities of the two tests and the need of a standardized approach for the future studies on epidemiology or toxicology of the {PM}.},
  keywords = {{FRANCE} ; {CHAMONIX}},
  booktitle = {},
  journal = {{A}tmospheric {C}hemistry and {P}hysics},
  volume = {18},
  numero = {13},
  pages = {9617--9629},
  ISSN = {1680-7316},
  year = {2018},
  DOI = {10.5194/acp-18-9617-2018},
  URL = {https://www.documentation.ird.fr/hor/fdi:010073221},
}