@article{fdi:010073118, title = {{R}ivers as carriers and potential sentinels for {B}urkholderia pseudomallei in {L}aos}, author = {{Z}immermann, {R}. {E}. and {R}ibolzi, {O}livier and {P}ierret, {A}lain and {R}attanavong, {S}. and {R}obinson, {M}. {T}. and {N}ewton, {P}. {N}. and {D}avong, {V}. and {A}uda, {Y}. and {Z}opfi, {J}. and {D}ance, {D}. {A}. {B}.}, editor = {}, language = {{ENG}}, abstract = {{B}urkholderia pseudomallei, causative agent of the often fatal disease melioidosis, dwells in tropical soils and has been found in freshwater bodies. {T}o investigate whether rivers are potential habitats or carriers for {B}. pseudomallei and to assess its geographical distribution in {L}aos, we studied 23 rivers including the {M}ekong, applying culture-based detection methods and {PCR} to water filters and streambed sediments. {B}. pseudomallei was present in 9% of the rivers in the dry season and in 57% in the rainy season. {W}e found the pathogen exclusively in {S}outhern and {C}entral {L}aos, and mainly in turbid river water, while sediments were positive in 35% of the {B}. pseudomallei-positive sites. {O}ur results provide evidence for a heterogeneous temporal and spatial distribution of {B}. pseudomallei in rivers in {L}aos with a clear north-south contrast. {T}he seasonal dynamics and predominant occurrence of {B}. pseudomallei in particle-rich water suggest that this pathogen is washed out with eroded soil during periods of heavy rainfall and transported by rivers, while river sediments do not seem to be permanent habitats for {B}. pseudomallei. {R}ivers may thus be useful to assess the distribution and aquatic dispersal of {B}. pseudomallei and other environmental pathogens in their catchment area and beyond.}, keywords = {{LAOS}}, booktitle = {}, journal = {{S}cientific {R}eports - {N}ature}, volume = {8}, numero = {}, pages = {art. 8674 [7p.]}, ISSN = {2045-2322}, year = {2018}, DOI = {10.1038/s41598-018-26684-y}, URL = {https://www.documentation.ird.fr/hor/fdi:010073118}, }