@article{fdi:010073114,
  title = {{D}ynamics of cholera epidemics from {B}enin to {M}auritania},
  author = {{M}oore, {S}. and {D}ongdem, {A}. {Z}. and {O}pare, {D}. and {C}ottavoz, {P}. and {F}ookes, {M}. and {S}adji, {A}. {Y}. and {D}zotsi, {E}. and {D}ogbe, {M}. and {J}eddi, {F}. and {B}idjada, {B}. and {P}iarroux, {M}. and {V}alentin, {O}. {T}. and {G}lele, {C}. {K}. and {R}ebaudet, {S}. and {S}ow, {A}. {G}. and {C}onstantin de {M}agny, {G}uillaume and {K}oivogui, {L}. and {D}unoyer, {J}. and {B}ellet, {F}. and {G}arnotel, {E}. and {T}homson, {N}. and {P}iarroux, {R}.},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ackground {T}he countries of {W}est {A}frica are largely portrayed as cholera endemic, although the dynamics of outbreaks in this region of {A}frica remain largely unclear. {M}ethodology/{P}rincipal findings {T}o understand the dynamics of cholera in a major portion of {W}est {A}frica, we analyzed cholera epidemics from 2009 to 2015 from {B}enin to {M}auritania. {W}e conducted a series of field visits as well as multilocus variable tandem repeat analysis and whole-genome sequencing analysis of {V}. cholerae isolates throughout the study region. {D}uring this period, {G}hana accounted for 52% of the reported cases in the entire study region (coastal countries from {B}enin to {M}auritania). {F}rom 2009 to 2015, we found that one major wave of cholera outbreaks spread from {A}ccra in 2011 northwestward to {S}ierra {L}eone and {G}uinea in 2012. {M}olecular epidemiology analysis confirmed that the 2011 {G}hanaian isolates were related to those that seeded the 2012 epidemics in {G}uinea and {S}ierra {L}eone. {I}nterestingly, we found that many countries deemed "cholera endemic" actually suffered very few outbreaks, with multi-year lulls. {C}onclusions/{S}ignificance {T}his study provides the first cohesive vision of the dynamics of cholera epidemics in a major portion of {W}est {A}frica. {T}his epidemiological overview shows that from 2009 to 2015, at least 54% of reported cases concerned populations living in the three urban areas of {A}ccra, {F}reetown, and {C}onakry. {T}hese findings may serve as a guide to better target cholera prevention and control efforts in the identified cholera hotspots in {W}est {A}frica.},
  keywords = {{BENIN} ; {MAURITANIE}},
  booktitle = {},
  journal = {{PL}o{S} {N}eglected {T}ropical {D}iseases},
  volume = {12},
  numero = {4},
  pages = {e0006379 [16 p.]},
  ISSN = {1935-2735},
  year = {2018},
  DOI = {10.1371/journal.pntd.0006379},
  URL = {https://www.documentation.ird.fr/hor/fdi:010073114},
}