@article{fdi:010073091,
  title = {{I}mpact of the use and efficacy of long lasting insecticidal net on malaria infection during the first trimester of pregnancy - a pre-conceptional cohort study in southern {B}enin},
  author = {{H}ounkonnou, {C}. and {D}jenontin, {A}. and {E}gbinola, {S}. and {H}oungbegnon, {P}. and {B}ouraima, {A}. and {S}oares, {C}. and {F}ievet, {N}adine and {A}ccrombessi, {M}. and {Y}ovo, {E}. and {B}riand, {V}al{\'e}rie and {C}ottrell, {G}illes},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ackground: {M}alaria in pregnancy is prevalent in {S}ub-{S}aharan {A}frica. {T}he first trimester of pregnancy is a critical period and the best preventive measure is {L}ong {L}asting {I}nsecticidal {N}ets ({LLIN}). {U}nfortunately, few studies have been conducted which focuses on the usage and efficacy of {LLIN} on malaria prevention during the first trimester. {M}ethods: {W}e assessed the use and effectiveness of {LLIN} in early pregnancy in {B}enin and its impact on malaria infection risk {W}e followed-up a cohort of 240 pregnant women from pre-conception to the end of the first trimester of pregnancy in {S}outhern {B}enin. {P}arasitological, maternal and {LLIN} data were actively collected before, at the beginning and end of the first trimester of pregnancy. {A} {C}ox regression model was used to determine the relationship between the time to onset of the first malaria infection and the use, physical integrity, and bio-efficacy of the {LLIN}, adjusted for relevant covariables. {R}esults: {T}he good use, good physical integrity and biological efficacy of {LLIN} were associated with a decreased risk of occurrence of the first malaria infection in early pregnancy ({HR}a = 038; (0.18-0.80); p < 0.001; {HR}a = 0.59; (0.29-1.19); p < 0.07; {HR}a = 0.97; (0.94-1.00); p < 0.04 respectively), after adjustment for other covariates. {P}rimi/secundigravidity and malaria infection before pregnancy were associated with a risk of earlier onset of malaria infection. {C}onclusion: {T}he classically used {LLIN}'s indicators of possession and use may not be sufficient to characterize the true protection of pregnant women in the first trimester of pregnancy. {I}ndicators of physical integrity and bio-efficacy should be integrated with those indicators in evaluation studies.},
  keywords = {{G}estational malaria ; {F}irst trimester ; {L}ong lasting impregnated nets ; {U}se ; {P}hysical integrity indicator ; {B}iological efficacy indicator ; {BENIN}},
  booktitle = {},
  journal = {{BMC} {P}ublic {H}ealth},
  volume = {18},
  numero = {},
  pages = {art. 683 [7 p.]},
  ISSN = {1471-2458},
  year = {2018},
  DOI = {10.1186/s12889-018-5595-2},
  URL = {https://www.documentation.ird.fr/hor/fdi:010073091},
}