%0 Journal Article
%9 ACL : Articles dans des revues avec comité de lecture répertoriées par l'AERES
%A El-Demerdash, A.
%A Moriou, C.
%A Martin, M. T.
%A Petek, Sylvain
%A Debitus, Cécile
%A Al-Mourabit, A.
%T Unguiculins A-C : cytotoxic bis-guanidine alkaloids from the French Polynesian sponge, Monanchora n. sp.
%D 2018
%L fdi:010073062
%G ENG
%J Natural Product Research
%@ 1478-6419
%K Monanchora ; Crambeidae ; unguiculin ; guanidine ; spermidine alkaloid
%K PACIFIQUE ; POLYNESIE FRANCAISE
%M ISI:000433990900004
%N 13
%P 1512-1517
%R 10.1080/14786419.2017.1385011
%U https://www.documentation.ird.fr/hor/fdi:010073062
%> https://www.documentation.ird.fr/intranet/publi/2018/06/010073062.pdf
%V 32
%W Horizon (IRD)
%X Two new acyclic bis-guanidine alkaloids, unguiculins B-C (2-3), were isolated from a French Polynesian sponge Monanchora n. sp. together with the known compound unguiculin A (1). Their structures were established by spectroscopic data interpretation and comparison with the literature. Unguiculins A-C displayed antiproliferative and cytotoxic efficacy against several human cancer cells with IC50 values in the micromolar range. [GRAPHICS] .
%$ 035 ; 052