@article{fdi:010073062, title = {{U}nguiculins {A}-{C} : cytotoxic bis-guanidine alkaloids from the {F}rench {P}olynesian sponge, {M}onanchora n. sp.}, author = {{E}l-{D}emerdash, {A}. and {M}oriou, {C}. and {M}artin, {M}. {T}. and {P}etek, {S}ylvain and {D}ebitus, {C}{\'e}cile and {A}l-{M}ourabit, {A}.}, editor = {}, language = {{ENG}}, abstract = {{T}wo new acyclic bis-guanidine alkaloids, unguiculins {B}-{C} (2-3), were isolated from a {F}rench {P}olynesian sponge {M}onanchora n. sp. together with the known compound unguiculin {A} (1). {T}heir structures were established by spectroscopic data interpretation and comparison with the literature. {U}nguiculins {A}-{C} displayed antiproliferative and cytotoxic efficacy against several human cancer cells with {IC}50 values in the micromolar range. [{GRAPHICS}] .}, keywords = {{M}onanchora ; {C}rambeidae ; unguiculin ; guanidine ; spermidine alkaloid ; {PACIFIQUE} ; {POLYNESIE} {FRANCAISE}}, booktitle = {}, journal = {{N}atural {P}roduct {R}esearch}, volume = {32}, numero = {13}, pages = {1512--1517}, ISSN = {1478-6419}, year = {2018}, DOI = {10.1080/14786419.2017.1385011}, URL = {https://www.documentation.ird.fr/hor/fdi:010073062}, }